A novel Mouse Model of Jansen's Metaphyseal Chondrodysplasia for analyzing disease mechanisms and candidate therapeutics

被引：0
|
作者：
Hoeppner, Jakob [1 ,2 ]
Firat, Damla [1 ,2 ]
Reyes, Monica [1 ,2 ]
Ramos-Torres, Karla [2 ,3 ]
Brugarolas, Pedro [2 ,3 ]
Yadav, Prem Swaroop [1 ,2 ]
Hanna, Patrick [1 ,2 ]
Wein, Marc [1 ,2 ]
Schipani, Ernestina [4 ]
Gardella, Thomas J. [1 ,2 ]
Jueppner, Harald [1 ,2 ]
机构：
[1] Massachusetts Gen Hosp, Endocrine Unit, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Dept Radiol, Gordon Ctr Med Imaging, Boston, MA 02114 USA
[4] Univ Penn, Perelman Sch Med, Dept Orthopaed Surg, Philadelphia, PA 19104 USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2024年 / 39卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1139
引用
收藏
页码：386 / 386
页数：1
相关论文
共 50 条
  • [21] An inducible MAO-B mouse model of Parkinson’s disease: a tool towards better understanding basic disease mechanisms and developing novel therapeutics
    Manish Chamoli
    Shankar J. Chinta
    Julie K. Andersen
    Journal of Neural Transmission, 2018, 125 : 1651 - 1658
  • [22] Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
    Yamagishi, Yoshiaki
    Kudo, Toshiyuki
    Oyumi, Masafumi
    Sakamoto, Yusuke
    Takahashi, Kazuki
    Akashi, Taiki
    Kobayashi, Shohei
    Kawakami, Takeaki
    Goda, Hitomi
    Sato, Yasuhiro
    Mimaki, Masakazu
    Kodama, Hiroko
    Munakata, Mitsutoshi
    Makino, Kosho
    Takahashi, Hideyo
    Fukami, Toshiro
    Ito, Kiyomi
    PHARMACEUTICAL RESEARCH, 2021, 38 (08) : 1335 - 1344
  • [23] Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
    Yoshiaki Yamagishi
    Toshiyuki Kudo
    Masafumi Oyumi
    Yusuke Sakamoto
    Kazuki Takahashi
    Taiki Akashi
    Shohei Kobayashi
    Takeaki Kawakami
    Hitomi Goda
    Yasuhiro Sato
    Masakazu Mimaki
    Hiroko Kodama
    Mitsutoshi Munakata
    Kosho Makino
    Hideyo Takahashi
    Toshiro Fukami
    Kiyomi Ito
    Pharmaceutical Research, 2021, 38 : 1335 - 1344
  • [24] A PTH Receptor Inverse Agonist (PTH-IA) in Patients with Jansen's Metaphyseal Chondrodysplasia: Rationale and Design for a Phase 1/2 Clinical Trial
    Jha, Smita
    Ninan, Anisha
    Gafni, Rachel
    Roszko, Kelly
    Ferreira, Carlos
    Lomash, Richa
    Stan, Rodica
    Ottinger, Elizabeth
    Gardella, Thomas
    Weinstein, Lee
    Jueppner, Harald
    Collins, Michael
    JOURNAL OF BONE AND MINERAL RESEARCH, 2023, 38 : 193 - 193
  • [25] CONSTITUTIVELY ACTIVE PTH/PTHRP RECEPTORS IN JANSEN METAPHYSEAL CHONDRODYSPLASIA (JMC) - IDENTIFICATION OF A NOVEL T410P MUTATION AND FURTHER CHARACTERIZATION OF POSITION-223
    SCHIPANI, E
    JENSEN, G
    PARFITT, AM
    JUPPNER, H
    JOURNAL OF BONE AND MINERAL RESEARCH, 1995, 10 : S173 - S173
  • [26] Novel therapeutics for Alzheimer’s disease
    Rudolph E. Tanzi
    Neurotherapeutics, 2008, 5 : 377 - 380
  • [27] Novel therapeutics for Alzheimer's disease
    Tanzi, Rudolph E.
    NEUROTHERAPEUTICS, 2008, 5 (03) : 377 - 380
  • [28] Psoriasis and Cardiovascular Disease: Novel Mechanisms and Evolving Therapeutics
    Weber, Brittany
    Merola, Joseph F.
    Husni, M. Elaine
    Di Carli, Marcelo
    Berger, Jeffrey S.
    Garshick, Michael S.
    CURRENT ATHEROSCLEROSIS REPORTS, 2021, 23 (11)
  • [29] Psoriasis and Cardiovascular Disease: Novel Mechanisms and Evolving Therapeutics
    Brittany Weber
    Joseph F. Merola
    M. Elaine Husni
    Marcelo Di Carli
    Jeffrey S. Berger
    Michael S. Garshick
    Current Atherosclerosis Reports, 2021, 23
  • [30] Correlating mutant gene expression with endoplasmic reticulum stress and the onset of disease phenotype in mouse models of metaphyseal chondrodysplasia type Schmid
    Kung, L.
    Rajpar, M. H.
    Briggs, M. D.
    Boot-Handford, R. P.
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2013, 94 (01) : A29 - A29
12345