Novel Pyrazolo[1,5-a]pyrimidine-3,5-diamines as nSMase2 Inhibitors

被引：0
|
作者：
Rong, Jian [1 ]
Liang, Steven H. [1 ]
机构：
[1] Emory Univ, Dept Radiol & Imaging Sci, Atlanta, GA 30322 USA
来源：
ACS MEDICINAL CHEMISTRY LETTERS | 2025年
关键词：
NEUTRAL SPHINGOMYELINASES;
D O I：
10.1021/acsmedchemlett.5c00134
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
This patent highlights novel pyrazolo[1,5-a]pyrimidine-3,5-diamines as neutral sphingomyelinase 2 (nSMase2) inhibitors. It provides detailed information on pyrazolo[1,5-a]pyrimidine-3,5-diamine compounds, their pharmaceutical composition, use, and potential therapeutic applications for nSMase2-related diseases.
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页数：2
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