Camel Milk and Oxidative stress: Therapeutic potential against metabolic syndrome diseases
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作者:
Musa, Khalid Hamid
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Qassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi ArabiaQassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi Arabia
Musa, Khalid Hamid
[1
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Hamad, Essam M.
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Qassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi ArabiaQassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi Arabia
Hamad, Essam M.
[1
]
Elnour, Ahmed A. M.
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Univ Malaysia Pahang Al Sultan Abdullah UMPSA, Fac Chem & Proc Engn Technol, Pekan, Pahang, Malaysia
Univ Malaysia Pahang Al Sultan Abdullah UMPSA, Ctr Excellence Adv Res Fluid Flow CARIFF, Pekan, Pahang, MalaysiaQassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi Arabia
Elnour, Ahmed A. M.
[2
,3
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机构:
[1] Qassim Univ, Coll Agr & Food, Dept Food Sci & Human Nutr, Buraydah 51452, Saudi Arabia
[2] Univ Malaysia Pahang Al Sultan Abdullah UMPSA, Fac Chem & Proc Engn Technol, Pekan, Pahang, Malaysia
[3] Univ Malaysia Pahang Al Sultan Abdullah UMPSA, Ctr Excellence Adv Res Fluid Flow CARIFF, Pekan, Pahang, Malaysia
Background: Camel milk (CM) has emerged as a potential therapeutic agent against oxidative stress (OS)-related disorders, particularly metabolic syndrome. CM contains bioactive compounds such as lactoferrin, alpha-lactalbumin, and Vitamin C, which contribute to its antioxidant properties. Objective: This review examines the antioxidant properties of CM and its bioactive components in combating OS and managing metabolic syndrome. Methods: A comprehensive literature review was conducted focusing on studies that explored the antioxidant properties of CM and its impact on OS and metabolic syndrome. Results: The findings indicated CM possesses significant antioxidant properties, mainly attributed to its bioactive compounds, which can inhibit the production of various reactive oxygen species (ROS), thereby reducing OS. Evidence suggests that CM enhances the body's antioxidative defense, improves insulin sensitivity, and supports liver and kidney function. CM's multifaceted approach shows promise as a therapeutic strategy for metabolic disorders related to OS. Conclusion: Considering its robust antioxidant qualities and capacity to regulate immune responses while enhancing metabolic health indicators, CM may be a valuable asset in the natural therapeutic repertoire to counter metabolic syndromes. Further clinical trials and research are essential to fully comprehend the therapeutic potential of CM, including dosage, long-term implications, and integration within extensive treatment schemes for metabolic syndromes and associated disorders. Recommendation: The use of CM to reduce OS requires further clinical studies to confirm its benefits and identify key compounds. Standardization of production and processing is essential for quality and safety, and research into potential risks and side effects is needed, especially for those with specific health conditions. Enhancing the accessibility, affordability, and sustainability of production methods is critical. Fortifying camel's milk with vitamins and minerals can improve its nutritional value.
机构:
Harry S Truman VA Med Ctr, Div Nephrol & Hypertens, Columbia, MO 65213 USA
Univ Missouri, Sch Med, Columbia, MO 65213 USA
Harry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65213 USAHarry S Truman VA Med Ctr, Div Nephrol & Hypertens, Columbia, MO 65213 USA
Whaley-Connell, Adam
Sowers, James R.
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Univ Missouri, Sch Med, Columbia, MO 65213 USA
Harry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65213 USAHarry S Truman VA Med Ctr, Div Nephrol & Hypertens, Columbia, MO 65213 USA
机构:
Harry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65201 USA
Univ Missouri, Sch Med, Columbia, MO USAHarry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65201 USA
Whaley-Connell, Adam
McCullough, Peter A.
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Providence Pk Hosp, St John Providence Hlth Syst, Dept Med, Cardiol Sect, Novi, MI USAHarry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65201 USA
McCullough, Peter A.
Sowers, James R.
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Harry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65201 USA
Univ Missouri, Sch Med, Columbia, MO USAHarry S Truman VA Med Ctr, Diabet & Cardiovasc Ctr, Columbia, MO 65201 USA
机构:
Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Wang, Xiao-Fang
Chen, Xue
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Chen, Xue
Tang, Yong
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Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Tang, Yong
Wu, Jian-Ming
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Wu, Jian-Ming
Qin, Da-Lian
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Qin, Da-Lian
Yu, Lu
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Yu, Lu
Yu, Chong-Lin
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Yu, Chong-Lin
Zhou, Xiao-Gang
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Zhou, Xiao-Gang
Wu, An-Guo
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Southwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China
Changsha Med Univ, Coll Pharm, Hunan Key Lab Res & Dev Novel Pharmaceut Preparat, Changsha 410219, Peoples R ChinaSouthwest Med Univ, Sch Pharm,Educ Minist Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Druggabi, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China