Evaluating the Genotoxicity of Small-Molecule Nitrosamines and Nitrosamine Drug Substance-Related Impurities in 2D and 3D HepaRG Cell Models

被引:0
|
作者
Xu, Hannah [1 ]
Seo, Ji-Eun [1 ]
Li, Xilin [1 ]
Mei, Nan [1 ]
Heflich, Robert [1 ]
Atrakchi, Aisar H. [2 ]
McGovern, Timothy J. [2 ]
Bruno, Karen L. Davis [2 ]
Guo, Xiaoqing [1 ]
机构
[1] US FDA, Div Genet & Mol Toxicol, Natl Ctr Toxicol Res, Jefferson, AR USA
[2] US FDA, Ctr Drug Evaluat & Res, Silver Spring, MD USA
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D O I
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中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
PS100
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收藏
页码:109 / 110
页数:2
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