Management of Pustular Psoriasis; The Way Ahead

被引：0

作者：

Parasramani, Shrichand G. ^{[1
]}

Kar, Bikash R. ^{[2
]}

Tahiliani, Sushil ^{[3
]}

Parthasarathi, Anchala ^{[4
]}

Neema, Shekhar ^{[5
]}

Ganguly, Satyaki ^{[6
]}

Sathishkumar, Dharshini ^{[7
]}

Venkatachalam, K. ^{[8
]}

Komeravelli, Haritha ^{[9
]}

Thomas, Jayakar ^{[9
,10
]}

机构：

[1] Lilavati Hosp, Dept DVL, Mumbai, Maharashtra, India

[2] IMS & SUM Hosp, Dept DVL, Bhubaneswar, Odisha, India

[3] PD Hinduja Hosp & Res Ctr, Dept DVL, Mumbai, Maharashtra, India

[4] Anchala Skin Inst & Res Ctr, Hyderabad, Telangana, India

[5] AFMC, Dept DVL, Pune, Maharashtra, India

[6] AIIMS, Dept DVL, Raipur, Chhattisgarh, India

[7] CMC, Dept DVL, Vellore, Tamil Nadu, India

[8] RIMS, Dept DVL, Srikakulam, Andhra Pradesh, India

[9] Apollo Hosp, Chennai, Tamil Nadu, India

[10] KK Child Trust Hosp, Chennai, Tamil Nadu, India

来源：

INDIAN JOURNAL OF DERMATOLOGY | 2024年 / 69卷 / 03期

关键词：

IL 36R inhibitors; pustular psoriasis; systemic treatment; treatment; GENERALIZED EXANTHEMATOUS PUSTULOSIS; ERYTHRODERMIC PSORIASIS; MUTATIONS; PREGNANCY; EFFICACY; SAFETY; INVOLVEMENT; DEFICIENCY;

D O I：

10.4103/ijd.ijd_165_24

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Pustular psoriasis is a specialized variant of psoriasis which can be life threatening if not treated at the earliest. The pathogenesis has been recently linked to the role of interleukin 36. Apart from the corticosteroids, systemic antipsoriatics like acitretin, cyclosporine and methotrexate have been used with some success though unpredictable. With recent identification of role of IL-36 in the pathogenesis of pustular psoriasis, biologics targeting the IL-36 receptors have been used to manage the situation with high degree of success. This narrative review deals with the recent concepts of pathogenesis of pustular psoriasis as well as the current management scenario.

引用

页码：241 / 248

页数：8

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