Clinical Effect of Hibiscus taiwanensis Extract on Women with Genitourinary Syndrome of Menopause

Objective:The deficiency of estrogen becomes clinically more overt over time and correlated with amounts of genitourinary syndromes of menopause (GSM). Our study aimed at examining the clinical effect of Hibiscus taiwanensis compound extract (HERCET (R)-w gel) on women with GSM.Subjects and Methods:This study included 31 patients with GSM symptoms. The treatment administered to patients included in this study was the daily use of vaginal treatment of HERCET (R)-w gel. Before, 3 months, and 6 months after HERCET (R)-w gel treatment, each patient's baseline characteristic data were collected.Results:Our data showed that HERCET (R)-w gel could significantly improve some index or questionnaire in urinary symptoms including the Urogenital Distress Inventory 6, the Vaginal Health Index, or pH value. It also showed a significant increase in sexual function after 6 months treatment of HERCET (R)-w.Conclusion:HERCET (R)-w on the women with GSM after 6 months could significantly improve GSM. It also showed an obvious progress of patients' sexual function in the Female Sexual Function Index score in the 6-month follow-up.