As a key component of wearable electronic devices, the human-computer interaction system is of great significance for realizing intelligent life. This study develops a smart sensing system with a flexible and stretchable single-electrode triboelectric nanogenerator (NZ-TENG) integrated touch sensing device and a voltage and current (UI) interaction interface. The NZ-TENG is composed of a conductive sponge coated with silicone rubber doped with NiMoO4/ZnCo MOF (350) (NZ) hybrid nanoparticles, effectively improving the friction layer's charge generation ability. When the NZ concentration is 0.05 wt% and the silicone rubber thickness is 2.0 mm, the NZ-TENG achieves excellent output performance, with open-circuit voltage, short-circuit current, and output power density reaching 150 V, 8 mu A and 1313 mW m- 2 respectively. This touch-sensing device has excellent tensile strength, hydrophobicity, safety, and skin-friendliness. The developed UI interaction interface provides various flexible rehabilitation training modes, targeting the patient's specific conditions for training. This assembled intelligent human-computer interaction has highly efficient biological signal monitoring and feedback, showing great potential for application in the field of rehabilitation medicine.