Renal metastasis of ovarian granulosa cell tumor

被引：4

作者：

Togashi, Kyo ^{[1
]}

Yoneyama, Tohru ^{[2
]}

Sutoh Yoneyama, Mihoko ^{[3
]}

Yamamoto, Hayato ^{[1
]}

Hatakeyama, Shingo ^{[1
]}

Yoneyama, Takahiro ^{[1
]}

Hashimoto, Yasuhiro ^{[1
]}

Futagami, Masayuki

Ohyama, Chikara ^{[1
]}

机构：

[1] Hirosaki Univ, Dept Urol, Grad Sch Med, 5 Zaifucho, Hirosaki, Aomori 0368562, Japan

[2] Hirosaki Univ, Dept Glycotechnol, Ctr Adv Med Res, Grad Sch Med, Hirosaki, Aomori, Japan

[3] Oyokyo Kidney Res Inst, Dept Canc Immunol & Cell Biol, Hirosaki, Aomori, Japan

来源：

IJU CASE REPORTS | 2022年 / 5卷 / 03期

关键词：

adult granulosa cell tumor; c134w mutation; FOXL2; renal metastasis; FOXL2; MUTATION;

D O I：

10.1002/iju5.12433

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: We would like to present a rare case of metastatic renal tumor. Case presentation: A 60-year-old woman presented to our department with a left renal tumor. She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15years ago, followed by left adnexal resection and postoperative chemotherapy with gemcitabine and paclitaxel 6years ago. She received six courses of gemcitabine and carboplatin to treat a stage IC clear cell adenocarcinoma of the ovary. The patient was diagnosed with the left renal tumor and underwent a laparoscopic left nephrectomy. Immunostaining was positive for alpha-inhibin and SF-1 and showed FOXL2 402C -> G (C134W) mutation. Finally, the patient was diagnosed with renal metastasis of a granulosa cell tumor. Conclusion: To our knowledge, this is a very rare case of renal metastasis of a granulosa cell tumor with the FOXL2 mutation in an adult.

引用

页码：186 / 190

页数：5

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