Safety and Efficacy of Olverembatinib (HQP1351) Combined with Lisaftoclax (APG-2575) in Children and Adolescents with Relapsed/Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (R/R Ph plus ALL): First Report from a Phase 1 Study

被引：0

作者：

Zhang, Jingliao ^{[1
]}

Wang, Junxia ^{[1
]}

Guo, Huanshan ^{[2
]}

Liu, Tianfeng ^{[1
]}

Zhang, Xiaoyan ^{[1
]}

Zhang, Ranran ^{[1
]}

Ruan, Min ^{[1
]}

Chang, Lixian ^{[3
]}

Liu, Xiaoming ^{[1
]}

Ren, Yuanyuan ^{[1
]}

Chen, Xia ^{[1
]}

Wang, Hengbang ^{[4
]}

Chen, Zi ^{[4
]}

Zhang, Yingchi ^{[3
]}

Chen, Yumei ^{[1
]}

Zhang, Li ^{[3
]}

Guo, Ye ^{[1
]}

Liu, Fang ^{[5
]}

Chen, Xiaojuan ^{[5
]}

Zou, Yao ^{[1
]}

Yang, Wenyu ^{[5
]}

Zhai, Yifan ^{[2
,4
]}

Zhu, Xiaofan ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, State Key Lab Expt Hematol, Inst Hematol & Blood Dis Hosp, Natl Clin Res Ctr Blood Dis,Haihe Lab Cell Ecosyst, Tianjin, Peoples R China

[2] Guangzhou Healthquest Pharm Co Ltd, Guangzhou, Peoples R China

[3] CAMS & PUMC, Inst Hematol & Blood Dis Hosp, State Key Lab Expt Hematol, Natl Clin Res Ctr Blood Dis,Haihe Lab Cell Ecosyst, Tianjin, Peoples R China

[4] Ascentage Pharma Suzhou Co Ltd, Suzhou, Peoples R China

[5] Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Natl Clin Res Ctr Blood Dis, Dept Pediat Hematol & Oncol,State Key Lab Expt Hem, Tianjin, Peoples R China

来源：

BLOOD | 2024年 / 144卷

关键词：

D O I：

10.1182/blood-2024-207035

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1443 / 1444

页数：2

共 31 条

[31] Long-Term Efficacy and Safety of Obecabtagene Autoleucel (obe-cel) in Adult Patients (pts) with Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia ([R/R B-ALL]; Pooled Analysis from ALLCAR19 and FELIX Phase Ib Studies) or Other B-cell Malignancies (ALLCAR19 Extension Study)
Roddie, Claire
Tholouli, Eleni
Shaughnessy, Paul
Jabbour, Elias
Logan, Aaron C.
Hodby, Katharine
Mountjoy, Luke
Bloor, Adrian John Clifton
Irvine, David
Linch, David C.
Orchard, Kim H.
Wilson, William
Popova, Bilyana
Dias, Juliana
Agliardi, Giulia
Spanswick, Victoria
Lowe, Helen
Mitsikakou, Marina
Charalambous, Eftychia
Dawes, Joanna
Raymond, Meera
Hu, Yanqing
Brugger, Wolfram
Pule, Martin A.
Park, Jae H.
Peggs, Karl
BLOOD, 2023, 142

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