This editorial article introduces the Special Issue entitled "Advanced Technologies and Applications in Computer Science and Engineering", which highlights a diverse range of contemporary research and technological advancements in these fields. The issue features selected contributions that explore cutting-edge innovations, including artificial intelligence, machine learning, quantum computing, the Internet of Things, and big data analytics, emphasizing their transformative impact on industry, science, and society. The articles address both theoretical advancements and practical applications, showcasing novel approaches to solving complex computational and engineering problems. Special attention is given to the challenges associated with the integration and implementation of these emerging technologies, including scalability, security, and ethical considerations. The selected studies present innovative solutions in key areas such as robotics, network security, cloud computing, and data-driven decision-making, contributing to the development of efficient, intelligent, and sustainable technological solutions. By bringing together a multidisciplinary perspective, this Special Issue aims to foster collaboration among researchers, engineers, and industry professionals, ultimately advancing the frontiers of computer science and engineering.