The application prospects of sacha inchi (Plukenetia volubilis linneo) in rheumatoid arthritis

被引:0
|
作者
Wang, Min [1 ,2 ]
Xiang, Yin-Hong [2 ]
Liu, Mei [2 ,3 ]
Jiang, Shan [1 ]
Guo, Jia-ying [1 ]
Jin, Xiao-yan [4 ]
Sun, Hui-feng [1 ]
Zhang, Ning [1 ,2 ]
Wang, Zhi-Gang [1 ]
Liu, Jian-xin [2 ,3 ]
机构
[1] Heilongjiang Univ Chinese Med, Sch Pharm, Harbin, Heilongjiang, Peoples R China
[2] Hunan Univ Med, Sino Pakistan Ctr Tradit Chinese Med, Sch Pharmaceut Sci, Sch Basic Med Sci,China Pakistan Int Sci & Technol, Huaihua, Hunan, Peoples R China
[3] Univ South China, Sch Pharmaceut Sci, Hengyang, Hunan, Peoples R China
[4] Xinjiang Med Univ, Sch Pharmaceut Sci, Urumqi, Xinjiang, Peoples R China
基金
中国国家自然科学基金;
关键词
<italic>Plukenetia volubilis</italic> linneo; sacha inchi; rheumatoid arthritis; inflammation; antioxidant; gut microbiota; POLYUNSATURATED FATTY-ACIDS; BIOLOGICAL-ACTIVITY; OIL; INFLAMMATION; L; EFFICACY; THERAPY; OMEGA-3-FATTY-ACIDS; ANTIOXIDANT; INFECTIONS;
D O I
10.3389/fphar.2024.1481272
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Sacha Inchi (Plukenetia volubilis L) (SI) is a traditional natural medicine from tropical rainforests of Amazon region in South America. As a raw material for edible oil, it has various pharmacological effects such as antioxidant, anti-inflammatory, hypolipidemia, and blood pressure lowering, which have attracted increasing attentions of pharmacists. This has prompted researchers to explore its pharmacological effects for potential applications in certain diseases. Among these, the study of its anti-inflammatory effects has become a particularly interesting topic, especially in rheumatoid arthritis (RA). RA is a systemic autoimmune disease, and often accompanied by chronic inflammatory reactions. Despite significant progress in its treatment, there is still an urgent need to find effective anti-RA drugs in regard to safety. This review summarizes the potential therapeutic effects of SI on RA by modulating gut microbiota, targeting inflammatory cells and pathways, and mimicking biologic antibody drugs, predicting the application prospects of SI in RA, and providing references for research aimed at using SI to treat RA.
引用
收藏
页数:20
相关论文
共 50 条
  • [31] Chemical composition of the shell of Sacha Inchi (Plukenetia volubilis) and alternatives for its use as agroindustrial byproduct
    Ricardo Benitez, B.
    Carolina Coronel, T.
    Hurtado Ordonez, Zully Adriana
    Jaime Martin, F.
    HOMBRE Y LA MAQUINA, 2015, (46): : 28 - 32
  • [32] Seed morphometry, in vitro germination and vegetative propagation in sacha inchi (Plukenetia volubilis L.)
    de Souza Cardoso, Arthur Antunes
    Gomes Lopes, Maria Teresa
    Ferreira Valente, Magno Savio
    Quisen, Regina Gaetano
    Maia Chaves, Francisco Celio
    REVISTA BRASILEIRA DE CIENCIAS AGRARIAS-AGRARIA, 2018, 13 (03):
  • [33] Synthesis of silver nanoparticles using Sacha inchi (Plukenetia volubilis L.) leaf extracts
    Kumar, Brajesh
    Smita, Kumari
    Cumbal, Luis
    Debut, Alexis
    SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2014, 21 (06) : 605 - 609
  • [34] Shade delayed flowering and decreased photosynthesis, growth and yield of Sacha Inchi (Plukenetia volubilis) plants
    Cai, Z. Q.
    INDUSTRIAL CROPS AND PRODUCTS, 2011, 34 (01) : 1235 - 1237
  • [35] Chemical composition of Sacha Inchi (Plukenetia volubilis L.) seeds and characteristics of their lipid fraction
    Gutierrez, Luis-Felipe
    Rosada, Lina-Maria
    Jimenez, Alvaro
    GRASAS Y ACEITES, 2011, 62 (01) : 76 - 83
  • [36] Oxidative stability and estimate of the shelf life of sacha inchi (Plukenetia volubilis L.) oil
    Rodriguez, Gilbert
    Villanueva, Eudes
    Glorio, Patricia
    Baquerizo, Mery
    SCIENTIA AGROPECUARIA, 2015, 6 (03) : 155 - 163
  • [37] Sacha inchi (Plukenetia volubilis L.) shell: an alternative source of phenolic compounds and antioxidants
    Chirinos, Rosana
    Necochea, Ornella
    Pedreschi, Romina
    Campos, David
    INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2016, 51 (04): : 986 - 993
  • [38] Reduction of Saturated Fat in Dark Chocolate using Sacha Inchi (Plukenetia volubilis) Oil Oleogel
    Ishak, Izzreen
    Ismail, Nur Ezzatul Balqish
    Yahaya, Nabilah Shahiqah
    Khaironi, Johari
    Musa, Nafisah
    Teh, Arnida Hani
    Abd Ghani, Maaruf
    JURNAL GIZI DAN PANGAN, 2024, 19 : 111 - 118
  • [39] Sacha Inchi (Plukenetia volubilis L.) Protein Hydrolysate as a New Ingredient of Functional Foods
    Lemus-Conejo, Ana
    Villanueva-Lazo, Alvaro
    Martin, Maria E.
    Millan, Francisco
    Millan-Linares, Maria C.
    FOODS, 2024, 13 (13)
  • [40] APPARENT ILEAL DIGESTIBILITY OF THE PROTEIN IN BROILERS PARTIALLY FED WITH SACHA INCHI (PLUKENETIA VOLUBILIS) CAKE
    Alcivar-Cobena, Jose L.
    Martinez-Perez, Madeleidy
    Figueroa-Toalombo, Maria F.
    V. Salazar-Salazar, Lizeth
    GRANJA-REVISTA DE CIENCIAS DE LA VIDA, 2024, 40 (02): : 141 - 148