US multicenter outcomes of endoscopic ultrasound-guided gallbladder drainage with lumen-apposing metal stents for acute cholecystitis

被引：0

作者：

David, Yakira ^{[1
]}

Kakked, Gaurav ^{[2
]}

Confer, Bradley ^{[3
]}

Shah, Ruchit ^{[4
]}

Khara, Harshit ^{[4
]}

Diehl, David L. ^{[3
]}

Krafft, Matthew RichardKrafft ^{[5
]}

Shah-Khan, Sardar M. ^{[6
]}

Nasr, John Y. ^{[7
]}

Benias, Petros ^{[8
]}

Trindad, Arvinde ^{[9
]}

Muniraj, Thiruvengada ^{[10
]}

Aslanian, Harry ^{[11
]}

Chahal, Prabhleen ^{[12
]}

Rodriguez, John ^{[12
]}

Adler, Douglas G. ^{[13
]}

Dubroff, Jason ^{[14
]}

De Latour, Rabi ^{[15
]}

Tzimas, Demetrios ^{[16
]}

Khanna, Lauren ^{[15
]}

Haber, Gregory ^{[15
]}

Goodman, Adam J. ^{[17
]}

Hoerter, Nicholas ^{[18
]}

Pandey, Nishi ^{[19
]}

Bakhit, Mena ^{[20
]}

Kowalski, Thomas E. ^{[21
]}

Loren, David ^{[22
]}

Chiang, Austin ^{[23
]}

Schlachterman, Alexander ^{[24
]}

Nieto, Jose ^{[25
]}

Deshmukh, Ameya ^{[26
]}

Ichkhanian, Yervant ^{[27
]}

Khashab, Mouen A. ^{[28
]}

El Halabi, Maan ^{[29
]}

Kwon, Richard S. ^{[30
]}

Prabhu, Anoop ^{[31
]}

Hernandez-Lara, Ariosto ^{[32
]}

Storm, Andrew

Berzin, Tyler M. ^{[33
]}

Ponero, John ^{[34
]}

Sethi, Amrita ^{[35
]}

Gonda, Tamas A. ^{[36
]}

Kushnir, Vladimir ^{[37
]}

Cosgrove, Natalie ^{[38
]}

Mullady, Daniel

Al-Shahrani, Abdullah ^{[39
]}

D'Souza, Lionel ^{[40
]}

Buscaglia, Jonathan ^{[41
]}

Bucobo, Juan Carlos ^{[42
]}

Rolston, Vineet ^{[43
]}

机构：

[1] Mayo Clin, Coll Med & Sci, Rochester, MN USA

[2] Rush Univ, Med Ctr, Chicago, IL USA

[3] Geisinger Med Ctr, Gastroenterol & Nutr, Danville, PA USA

[4] Geisinger Med Ctr, Danville, PA USA

[5] Ruby Mem Hosp, Morgantown, WV 26506 USA

[6] Rutgers Robert Wood Johnson Med Sch, Gastroenterol, New Brunswick, NJ USA

[7] West Virginia Univ, Sch Med, Digest Dis, Morgantown, WV USA

[8] Rutgers State Univ, New Brunswick, NJ USA

[9] North Shore Long Isl Jewish Med Ctr, New Hyde Pk, NY USA

[10] Yale Univ, New Haven, CT USA

[11] Yale Univ, Sch Med, Dept Med, Sect Digest Dis, New Haven, CT USA

[12] Cleveland Clin, Cleveland, OH USA

[13] Univ Utah, Sch Med, Gastroenterol, Salt Lake City, UT 84112 USA

[14] Univ Utah Hlth, Salt Lake City, UT USA

[15] NYU Langone Hlth, New York, NY USA

[16] Northwell Hlth, New Hyde Pk, NY USA

[17] NYU, Langone Med Ctr, Gastroenterol, New York, NY USA

[18] Icahn Sch Med Mt Sinai, New York, NY USA

[19] Bayonne Med Ctr, Bayonne, NJ USA

[20] Brown Univ, Warren Alpert Med Sch, Providence, RI USA

[21] Thomas Jefferson Univ, Gastroenterol, Ctr City Campus, Philadelphia, PA USA

[22] Fox Chase Canc Ctr, Philadelphia, PA USA

[23] Thomas Jefferson Univ Hosp, JeffSTAT Educ Ctr, Philadelphia, PA 19107 USA

[24] Univ Florida, Div Gastroenterol Hepatol & Nutr, Gainesville, FL USA

[25] Borland Groover Clin, Gastroenterol, Jacksonville, FL USA

[26] ST LOUIS UNIV, St. Louis, MO USA

[27] Indiana Univ, Bloomington, IN 47405 USA

[28] Johns Hopkins Univ Hosp, Gastroenterol, Baltimore, MD USA

[29] Tufts Med Ctr, Boston, MA USA

[30] Univ Michigan, Internal Med, Ann Arbor, MI USA

[31] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[32] Mayo Fdn Med Educ & Res, Rochester, MN USA

[33] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Gastroenterol, Boston, MA USA

[34] Columbia Univ, Digest & Liver Dis, Med Ctr, New York, NY USA

[35] Columbia Presbyterian Med Ctr, New York, NY 10032 USA

[36] Columbia Univ, Digest & Liver Dis, Med Ctr, New York, NY USA

[37] Washington Univ St Louis, St Louis, MO USA

[38] Thomas Jefferson Univ, Gastroenterol & Hepatol, Philadelphia, PA 19107 USA

[39] CU Anschutz Med Campus, Aurora, CO USA

[40] Stony Brook Univ Hosp, Stony Brook, NY USA

[41] SUNY Stony Brook, Stony Brook, NY USA

[42] North Shore Univ Hosp, Manhasset, NY USA

[43] Mem Sloan Kettering Canc Ctr, New York, NY USA

[44] Methodist Dallas Med Ctr, Gastroenterol, Dallas, TX USA

[45] HCA Florida Aventura Hosp & Med Ctr, Aventura, FL USA

[46] Icahn Sch Med Mt Sinai, Med, New York, NY USA

[47] Icahn Sch Med Mt Sinai, Dr Henry D Janowitz Div Gastroenterol, New York, NY USA

[48] Catholic Hlth St Francis Hosp & Heart Ctr, Roslyn, NY USA

来源：

ENDOSCOPY INTERNATIONAL OPEN | 2025年 / 13卷

关键词：

Endoscopic ultrasonography; Intervention EUS; Biliary tract; Quality and logistical aspects; Performance and complications; PERCUTANEOUS CHOLECYSTOSTOMY; ACALCULOUS CHOLECYSTITIS; STRATEGIES; MANAGEMENT;

D O I：

10.1055/a-2495-5542

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background and study aims EUS-guided gallbladder drainage (EUS-GBD) using lumen apposing metal stents (LAMS) has excellent technical and short-term clinical success for acute cholecystitis (AC). The goals of this study were to determine the long-term clinical outcomes and adverse events (AEs) of EUS-GBD with LAMS. Patients and methods A multicenter, retrospective study was conducted at 18 US tertiary care institutions. Inclusion criteria: any AC patient with attempted EUS-GBD with LAMS and minimum 30-day post-procedure follow-up. Long-term clinical success was defined as absence of recurrent acute cholecystitis (RAC) > 30 days and long-term AE was defined as occurring > 30 days from the index procedure. Results A total of 109 patients were included. Technical success was achieved in 108 of 109 (99.1%) and initial clinical success in 106 of 109 (97.2%). Long-term clinical success was achieved in 98 of 109 (89.9%) over a median follow-up of 140 days (range 30-1188). On multivariable analysis (MVA), acalculous cholecystitis (odds ratio [OR] 15.93, 95% confidence interval [CI] 1.22-208.52, P = 0.04) and the occurrence of a LAMS-specific AE (OR 63.60, 95% CI 5.08-799.29, P <0.01) were associated with RAC. AEs occurred in 38 of 109 patients (34.9%) at any time, and in 10 of 109 (9.17%) > 30 days from the index procedure. Most long-term AEs (7 of 109; 6.42%) were LAMS-specific. No technical or clinical factors were associated with occurrence of AEs. LAMS were removed in 24 of 109 patients (22%). There was no difference in RAC or AEs whether LAMS was removed or not. Conclusions EUS-GBD with LAMS has a high rate of long-term clinical success and modest AE rates in patients with AC and is a reasonable destination therapy for high-risk surgical candidates.

引用

页数：10

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