Carcinoma Ex Pleomorphic Adenoma of the Palate-A Rare Encounter

Background: Carcinoma ex pleomorphic adenoma (Ca ex PA) is a rare malignant transformation of a benign pleomorphic adenoma, constituting about 6.2% of mixed tumors.The malignant component of Ca ex PA is most often adenocarcinoma not otherwise specified. Case Presentation: This case report presents a 45-year-old male with an ulcerative lesion on the hard palate, initially suspected to be a minor salivary gland tumor or squamous cell carcinoma. Clinical examination revealed a non-healing ulcer and a palpable submandibular lymph node. Histopathological analysis of the biopsy showed features consistent with highgrade malignant minor salivary gland tumor, with immunohistochemical staining confirming Ca ex PA. Management and Prognosis: The surgical resection was done with regular follow-up. Conclusion: This tumor type, often found in the parotid glands, occasionally arises in minor salivary glands such as the hard palate. The patient's history lacked contributory factors, and the tumor presented insidiously. The case underscores the diagnostic complexity of Ca ex PA due to its varied presentation and histological features, emphasizing the importance of comprehensive diagnostic evaluation.The primary treatment involved surgical excision, with the necessity of regular follow-up to monitor for recurrence. Early diagnosis and intervention are crucial for improving prognosis and survival in patients with this aggressive malignancy.