Exploring ocular disorders in Parkinson's disease: A comprehensive review and future perspectives

被引:0
|
作者
Thacker, Minal [1 ]
Wong, Ka Ying [1 ,2 ]
Zhou, Liping [1 ,3 ,4 ,5 ]
Liu, Juewen [1 ,2 ]
Wong, Man-Sau [1 ,4 ,6 ]
机构
[1] Ctr Eye & Vis Res CEVR, 17W Hong Kong Sci Pk, Hong Kong, Peoples R China
[2] Univ Waterloo, Waterloo Inst Nanotechnol, Dept Chem, Waterloo, ON N2L 3G1, Canada
[3] Hong Kong Polytech Univ, Sch Optometry, Kowloon, Hong Kong, Peoples R China
[4] Hong Kong Polytech Univ, Res Ctr Chinese Med Innovat, Kowloon, Hong Kong, Peoples R China
[5] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China
[6] Hong Kong Polytech Univ, Dept Food Sci & Nutr, Kowloon, Hong Kong, Peoples R China
基金
中国国家自然科学基金;
关键词
Parkinson's disease; Ocular diseases; Clinical management; Pathophysiological mechanism; MACULAR DEGENERATION; DIABETIC-RETINOPATHY; VISUAL DYSFUNCTION; OXIDATIVE STRESS; INCREASED RISK; CORNEAL SENSITIVITY; NEUROTROPHIC FACTOR; CATARACT-SURGERY; CELL-DEATH; GLAUCOMA;
D O I
10.1016/j.exer.2024.110225
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Parkinson's disease (PD) is a multifaceted neurodegenerative disorder characterized by predominantly motor symptoms. However, recent research has broadened our understanding of PD by revealing its impact on nonmotor functions, including ocular manifestations. This review explored the intricate relationship between PD and ocular health, shedding light on the mechanisms underlying common ocular diseases such as dry eye disease, cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy. It also underscores the importance of recognizing ocular manifestations as potential early markers of PD, as well as their impact on patients' daily activities, necessitating prompt identification and intervention to prevent complications and enhance the overall quality of life. Furthermore, future research should prioritize unraveling the potential association between PD and other prevalent ocular diseases, such as myopia, to formulate effective treatment strategies.
引用
收藏
页数:9
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