PACAP inhibition as a new mode of action for migraine

被引：0
|
作者：
Klein, Friederike
机构：
来源：
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT | 2025年 / 150卷 / 06期
关键词：
D O I：
10.1055/a-2464-9044
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
If other measures and medications for migraine prophylaxis are not sufficient, inhibitors of CGRP (calcitonin gene-related peptide) are currently an important option. However, many sufferers do not respond adequately to these medications either. Inhibiting the signaling molecule pituitary adenylate cyclase-activating polypeptide (PACAP) could be a new approach to migraine prophylaxis.
引用
收藏
页码：247 / 248
页数：2
相关论文
共 50 条
  • [31] PACAP27 induces migraine-like attacks in migraine patients
    Ghanizada, Hashmat
    Al-Karagholi, Mohammad Al-Mahdi
    Arngrim, Nanna
    Olesen, Jes
    Ashina, Messoud
    CEPHALALGIA, 2020, 40 (01) : 57 - 67
  • [32] NEW ANTIANDROGENS AND THEIR MODE OF ACTION
    NEUMANN, F
    SCHENCK, B
    JOURNAL OF REPRODUCTION AND FERTILITY, 1976, : 129 - +
  • [33] MODE OF ACTION OF A NEW COLICIN
    DEZWAIG, RN
    VITELLIF.J
    FEBS LETTERS, 1973, 29 (03): : 318 - 322
  • [34] NEW MODE OF ACTION FOR LACTULOSE
    VANLEEUWEN, PAM
    VANBERLO, CLH
    SOETERS, PB
    LANCET, 1988, 1 (8575-6): : 55 - 56
  • [35] CGRP and migraine: Could PACAP play a role too?
    Kaiser, Eric A.
    Russo, Andrew F.
    NEUROPEPTIDES, 2013, 47 (06) : 451 - 461
  • [36] Shared and independent roles of CGRP and PACAP in migraine pathophysiology
    Adisa Kuburas
    Andrew F. Russo
    The Journal of Headache and Pain, 24
  • [37] Shared and independent roles of CGRP and PACAP in migraine pathophysiology
    Kuburas, Adisa
    Russo, Andrew F.
    JOURNAL OF HEADACHE AND PAIN, 2023, 24 (01):
  • [38] Kynurenines and PACAP in Migraine: Medicinal Chemistry and Pathogenetic Aspects
    Tajti, Janos
    Szok, Delia
    Nagy-Grocz, Gabor
    Tuka, Bernadett
    Petrovics-Balog, Anna
    Toldi, Jozsef
    Vecsei, Laszlo
    CURRENT MEDICINAL CHEMISTRY, 2017, 24 (13) : 1332 - 1349
  • [39] PACAP-induced migraine: a possible CNS effect?
    Tfelt-Hansen, Peer Carsten
    BRAIN, 2014, 137
  • [40] PACAP hybrid: A new PACAP receptor antagonist
    Pisegna, JR
    Leyton, J
    Coelho, T
    Hida, T
    Jakowlew, S
    Birrer, M
    Fridkin, M
    Gozes, I
    Moody, TW
    LIFE SCIENCES, 1997, 61 (06) : 631 - 639
12345