Prognostic significance of electrophysiological study in drug-induced type-1 Brugada syndrome: a brief systematic review

被引：2

作者：

Mascia, Giuseppe ^{[1
]}

Brugada, Josep ^{[2
,3
,4
,5
,6
]}

Barca, Luca ^{[7
]}

Benenati, Stefano ^{[7
]}

Della Bona, Roberta ^{[1
]}

Scara, Antonio ^{[8
]}

Russo, Vincenzo ^{[9
]}

Arbelo, Elena ^{[3
,4
,5
,6
]}

Di Donna, Paolo ^{[1
]}

Porto, Italo ^{[1
,7
]}

机构：

[1] IRCCS, Osped Policlin San Martino, Cardiovasc Dis Unit, Genoa, Italy

[2] Hosp St Joan de Deu, Inherited Cardiac Dis & Sudden Death Unit, Arrhythmia, Esplugas De Llobregat, Spain

[3] Univ Barcelona, Hosp Clin, Cardiol Dept, Arrhythmia Sect, Barcelona, Spain

[4] Inst Invest August Pi & Sunyer IDIBAPS, IDIBAPS, Barcelona, Spain

[5] Ctr Invest Biomed Red Enfermedades Cardiovasc CIBE, Madrid, Spain

[6] European Reference Network Rare Low Prevalence & C, Amsterdam, Netherlands

[7] Univ Genoa, Dept Internal Med, Genoa, Italy

[8] San Carlo Nancy Hosp, Dept Cardiol, Rome, Italy

[9] Univ Campania, Monaldi Hosp, Dept Med Translat Sci, Cardiol Unit, Naples, Italy

来源：

JOURNAL OF CARDIOVASCULAR MEDICINE | 2024年 / 25卷 / 11期

关键词：

Brugada syndrome; electrophysiological study; risk assessment; sudden cardiac death; PROGRAMMED VENTRICULAR STIMULATION; PREVIOUS CARDIAC-ARREST; LONG-TERM PROGNOSIS; ELECTROCARDIOGRAPHIC PATTERN; RISK STRATIFICATION; DEATH;

D O I：

10.2459/JCM.0000000000001665

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BackgroundRisk stratification in drug-induced type-1 Brugada syndrome (BrS) patients is challenging. The role of electrophysiological study (EPS) is debated as the majority of drug-induced type-1 BrS patients would not be studied according to the latest recommendations.MethodsA complete systematic literature search was performed to gauge the EPS role in this population. Three subgroups were defined: positive-EPS group, negative-EPS group, no-EPS group.ResultsAmong 1318 drug-induced type-1 BrS patients, no significant difference in the incidence rate of arrhythmic events was observed between groups (I2 = 45%, P for subgroup difference = 0.10) during a mean follow-up of 5.1 years, also considering symptomatic status.ConclusionIn long-term follow-up of drug-induced type-1 BrS patients, EPS does not seem to aid prognostic stratification.

引用

页码：775 / 780

页数：6

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