Advances and challenges in chimeric antigen receptor-natural killer cell immunotherapy for cancer

被引：0
|
作者：
Rafei, Hind [1 ]
Rezvani, Katayoun [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat & Cellular Therapy, Houston, TX 77030 USA
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2025年 / 206卷 / 02期
基金：
美国国家卫生研究院;
关键词：
CAR-NK; immunotherapy; NK cells;
D O I：
10.1111/bjh.19939
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chimeric antigen receptor (CAR)-natural killer (NK)-cell therapy has emerged as a promising strategy in the treatment of haematological malignancies and solid cancers. Leveraging the innate immune properties of NK cells, CAR-NK-cell therapies offer potential advantages for cell therapy, including safety of use in the allogeneic setting and reduced risk of toxicity. This Nutshell provides an overview of the latest advancements in CAR-NK-cell therapy and the challenges that remain.
引用
收藏
页码：443 / 446
页数：4
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