Impact of pomegranate juice consumption on glycemic indices: a systematic review and meta-analysis

Purpose - The purpose of this meta-analysis was to examine the effect of pomegranate juice (PJ) intake on glycemic control in adults. Design/methodology/approach - Materials and methods: PubMed (Medline), ISI Web of Science, Cochrane Library and Scopus databases, measuring glucose and/or insulin and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) in adults, were searched from inception to December 11, 2021. Moreover, to examine whether grouping factors influenced heterogeneity between research results, subgroup analysis was used. Findings - This meta-analysis showed that PJ intake reduced HOMA-IR significantly, especially if =250 mL was used. This reducing effect remained significant in females, nondiabetic patients and unhealthy subjects. Originality/value - The authors believe the presented data would be highly motivating and of a wide readership for the readers of your journal, and this paper stimulating a surge of research on the impact of PJ consumption on glycemic indices.