The growing demand for flexible and efficient thermal management solutions has driven the development of advanced Joule heating textiles with multifunctional capabilities. This study introduces a novel dual-functional MXene/polyaniline-coated cotton woven fabric designed for both efficient Joule heating and wearable strain sensing applications. Polyaniline was deposited onto cotton fabrics via in-situ chemical polymerization, followed by MXene nanosheets coating through a dip-coating process. The structural, electrical, and electrothermal properties of the fabricated polyaniline/cotton, MXene/cotton with varying coating cycles, and MXene/polyaniline cotton fabrics were thoroughly evaluated. The results demonstrated that increasing the MXene coating cycles significantly reduced the surface resistance, with the polyaniline-coated fabric featuring two MXene layers achieving an ultra-low resistance of 11.9 ± 1.2 Ω/sq. The MXene/polyaniline fabric exhibited exceptional Joule heating performance, reaching 66.2 °C at 5 V and exceeding 230 °C at 15 V within 40 seconds, outperforming many previously reported materials. Furthermore, the sample displayed remarkable durability and stability in its generated temperature. The strain-sensing capability of these fabrics was also investigated, revealing a negative resistance response to strain, enabling effective detection of human motion.These findings highlight the potential of MXene/polyaniline textiles as next-generation wearable electronics, with applications in personal thermal management, thermal therapy, de-icing, and real-time motion monitoring. © 2025 Elsevier B.V.