TUTOR: A MULTICENTER, PHASE 1 TRIAL OF TUCATINIB, TRASTUZUMAB, AND CAPECITABINE WITH STEREOTACTIC RADIOSURGERY FOR BRAIN METASTASES FROM HER-2 POSITIVE BREAST CANCER

被引:0
|
作者
Ahluwalia, M. S. [1 ,2 ]
Ozair, A. [1 ,3 ]
Bardhan, M. [1 ]
Bellur, S. S. [1 ]
Perche, D. C. [1 ]
Starosciak, A. K. [1 ]
Khosla, A. A. [1 ]
Leon-Ariza, D. S. [1 ]
Rubens, M. [1 ]
Odia, Y. [1 ]
Mehta, M. P. [1 ,2 ]
Kotecha, R. R. [1 ,2 ]
McDermott, M. W. [2 ,4 ]
Leon, A. C. S. [1 ]
Mahtani, R. [1 ]
Peereboom, D. M. [5 ]
机构
[1] Baptist Hlth South Florida, Miami Canc Inst, Miami, FL USA
[2] Florida Int Univ, Herbert Wertheim Coll Med, Miami, FL USA
[3] Univ Maryland Med, Dept Neurosurg, Baltimore, MD USA
[4] Baptist Hlth South Florida, Miami Neurosci Inst, Miami, FL USA
[5] Cleveland Clin, Cleveland, OH USA
关键词
D O I
10.1093/neuonc/noae144.148
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P06.11.A
引用
收藏
页码:V47 / V47
页数:1
相关论文
共 50 条
  • [41] HER2CLIMB-04: phase 2 trial of tucatinib plus trastuzumab deruxtecan in patients with HER2+locally advanced or metastatic breast cancer with and without brain metastases (trial in progress)
    Hamilton, Erika
    Carey, Lisa
    Ramos, Jorge
    Chen, Yiyi
    Krop, Ian
    CANCER RESEARCH, 2022, 82 (04)
  • [42] Results of stereotactic radiosurgery for brain metastases from breast cancer
    Suh, J. H.
    Neyman, A.
    Elson, P.
    Chao, S. T.
    Vogelbaum, M. A.
    Angelov, L.
    Barnett, G. H.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (03): : S262 - S262
  • [43] Phase 2 trial of tucatinib plus trastuzumab deruxtecan in patients with HER2+locally advanced or metastatic breast cancer with and without brain metastases (HER2CLIMB-04, trial in progress).
    Krop, Ian E.
    Carey, Lisa A.
    Ramos, Jorge
    Chen, Yiyi
    Hamilton, Erika P.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [44] TBCRC049: A phase II non-randomized study to assess the safety and efficacy of the combination of tucatinib and trastuzumab and capecitabine for treatment of leptomeningeal metastases in HER2 positive breast cancer TBCRC049: A phase II non-randomized study to assess the safety and efficacy of the combination of tucatinib and trastuzumab and capecitabine for treatment of leptomeningeal metastases in HER2 positive breast cancer
    Murthy, Rashmi K.
    O'Brien, Barbara J.
    Hess, Ken R.
    Navin, Nick
    Johnson, Jason
    Gule-Monroe, Maria
    Leone, Jose P.
    Specht, Jennifer
    Melisko, Michelle
    Morikawa, Aki
    Storniolo, Anna M.
    Brufsky, Adam
    Pohlmann, Paula R.
    Park, Deric M.
    Park, Ben H.
    Krop, Ian
    Lin, Nancy U.
    Wolff, Antonio
    Forerro-Torres, Andres
    Stringer-Reasor, Erica
    CANCER RESEARCH, 2020, 80 (04)
  • [45] Tucatinib vs placebo added to trastuzumab and capecitabine for patients with previously treated HER2+metastatic breast cancer (MBC) with brain metastases (BM) (HER2CLIMB)
    Mueller, V
    Lin, N.
    Murthy, R.
    Anders, C.
    Borges, V
    Hurvitz, S.
    Loi, S.
    Abramson, V
    Bedard, P.
    Oliveira, M.
    Zelnak, A.
    Di Giovanna, M.
    Bachelot, T.
    Chien, A. J.
    O'Regan, R.
    Wardley, A.
    Carey, L.
    McGoldrick, S.
    An, X.
    Winer, E. P.
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 (SUPPL 4) : 161 - 161
  • [46] The contribution of Her-2 to breast cancer brain metastases
    Bronder, Julie L.
    Palmieri, Diane
    Yoneda, Toshiyuki
    Weil, Robert J.
    Stark, Andreas M.
    Mehdorn, H. Maximilian
    Davis, Sean
    Walker, Robert
    Meltzer, Paul S.
    Steeg, Patricia S.
    CANCER RESEARCH, 2006, 66 (08)
  • [47] Role of HER2 status in the treatment for brain metastases arising from breast cancer with stereotactic radiosurgery
    Moses Tam
    Ashwatha Narayana
    Shahzad Raza
    Saroj Kunnakkat
    John G. Golfinos
    Erik C. Parker
    Yelena Novik
    Medical Oncology, 2014, 31
  • [48] Risk of radionecrosis in HER2-positive breast cancer with brain metastasis receiving trastuzumab emtansine (T-DM1) and brain stereotactic radiosurgery
    Chun, Seok-Joo
    Kim, Kyubo
    Kim, Yong Bae
    Paek, Sun Ha
    Lee, Kyung-Hun
    Song, Jin-Ho
    Jang, Won Il
    Kim, Tae Hyun
    Salvestrini, Viola
    Meattini, Icro
    Livi, Lorenzo
    Shin, Kyung Hwan
    RADIOTHERAPY AND ONCOLOGY, 2024, 199
  • [49] HER-2 overexpressed breast cancer and brain metastases
    Lichinitser, M.
    Ganshina, I.
    Zhukova, L.
    Lud, H.
    Meluzova, O.
    BREAST, 2007, 16 : S19 - S19
  • [50] Role of HER2 status in the treatment for brain metastases arising from breast cancer with stereotactic radiosurgery
    Tam, Moses
    Narayana, Ashwatha
    Raza, Shahzad
    Kunnakkat, Saroj
    Golfinos, John G.
    Parker, Erik C.
    Novik, Yelena
    MEDICAL ONCOLOGY, 2014, 31 (02)