Orthogonal tandem catalysis involving Au(<sc>i</sc>)-hydroacyloxylation and Rh(<sc>i</sc>)-hydroformylation reactions

We report an orthogonal tandem catalysis (OTC) involving Au(i)-hydroacyloxylation and Rh(i)-hydroformylation highlighting their compatibility when these metals are employed in a reaction of homogeneous catalysis. Moreover, this OTC allows the synthesis of different carbaldehydes. Several derivatizations were performed at the end of the OTC procedure, giving access to two series of alcohol and oxime derivatives. 31P NMR experiments and kinetic studies carried out on the OTC allowed a detailed understanding of the catalytic cycles involved, highlighting the competitive ligand coordination between the gold and rhodium catalysts.