Combined Effect of Obeticholic Acid and Bezafibrate in Patients With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid: 6-Month Results From a Phase 2 Trial

被引:0
|
作者
Ballard, Meha [1 ]
Jones, David E. [2 ]
Louvet, Alexandre [3 ]
Corpechot, Christophe [4 ]
Hejda, Vaclav [5 ]
Zou, Heng [1 ]
Civitarese, Antonio [1 ]
Villamil, Alejandra [6 ]
Nevens, Frederick [7 ]
机构
[1] Intercept Pharmaceut Inc, Morristown, NJ USA
[2] Newcastle Univ, Newcastle Upon Tyne, England
[3] Univ Hosp, Lille, Nord Pas De Cal, France
[4] St Antoine Hosp, Reference Ctr Inflammatory Biliary Dis & Autoimmun, Paris, Ile De France, France
[5] Univ Hosp, Plzen, Czech Republic
[6] Hosp Italiano Buenos Aires, Buenos Aires, Argentina
[7] Univ Hosp KU Leuven, Leuven, Vlaams Brabant, Belgium
来源
AMERICAN JOURNAL OF GASTROENTEROLOGY | 2024年 / 119卷 / 10S期
关键词
D O I
10.14309/01.ajg.0001028820.02913.42
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
S113
引用
收藏
页码:S82 / S83
页数:2
相关论文
共 50 条
  • [1] Combined effect of obeticholic acid and bezafibrate in patients with primary biliary cholangitis and inadequate response or intolerance to ursodeoxycholic acid: 6-month results from a phase 2 trial
    Jones, David E.
    Louvet, Alexandre
    Corpechot, Christophe
    Hejda, Vaclav
    Zou, Heng
    Civitarese, Antonio
    Villamil, Alejandra
    Nevens, Frederik
    JOURNAL OF HEPATOLOGY, 2024, 80 : S91 - S91
  • [2] COMBINED EFFECT OF OBETICHOLIC ACID AND BEZAFIBRATE IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS AND INADEQUATE RESPONSE TO OR INTOLERANCE OF URSODEOXYCHOLIC ACID: RESULTS FROM TWO PHASE 2 CLINICAL TRIALS
    Levy, Cynthia
    Hejda, Vaclav
    Louvet, Alexandre
    Younes, Ziad
    Mendizabal, Manuel
    Bonder, Alan
    Zou, Heng
    Civitarese, Antonio
    Villamil, Alejandra
    Nevens, Frederik
    HEPATOLOGY, 2024, 79 (02) : E52 - E52
  • [3] Bezafibrate for primary biliary Cholangitis "Bezafibrate in combination with ursodeoxycholic acid in primary biliary cholangitis (BEZURSO) trial"
    Klose, G.
    Nitschmann, S.
    INTERNIST, 2018, 59 (12): : 1344 - 1346
  • [4] Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid
    Hirschfield, Gideon M.
    Mason, Andrew
    Luketic, Velimir
    Lindor, Keith
    Gordon, Stuart C.
    Mayo, Marlyn
    Kowdley, Kris V.
    Vincent, Catherine
    Bodhenheimer, Henry C., Jr.
    Pares, Albert
    Trauner, Michael
    Marschall, Hanns-Ulrich
    Adorini, Luciano
    Sciacca, Cathi
    Beecher-Jones, Tessa
    Castelloe, Erin
    Boehm, Olaf
    Shapiro, David
    GASTROENTEROLOGY, 2015, 148 (04) : 751 - U347
  • [5] COST-EFFECTIVENESS ANALYSIS OF OBETICHOLIC ACID FOR THE TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) PATIENTS WITH INADEQUATE RESPONSE OR INTOLERANCE TO URSODEOXYCHOLIC ACID (UDCA) IN FRANCE
    Baschet, L.
    Bourguignon, S.
    Tison, A.
    VALUE IN HEALTH, 2017, 20 (09) : A556 - A556
  • [6] Determinants of the effectiveness of bezafibrate combined with ursodeoxycholic acid in patients with primary biliary cholangitis
    Matsumoto, Kosuke
    Hirohara, Junko
    Takeuchi, Akihito
    Miura, Ryo
    Asaoka, Yoshinari
    Nakano, Toshiaki
    Tanaka, Atsushi
    HEPATOLOGY RESEARCH, 2023, 53 (10) : 989 - 997
  • [7] Bezafibrate improves the effect of obeticholic acid on cholestasis in patients with primary biliary cholangitis
    Smets, Lena
    Liliane, Schrijvers
    Hannelie, Korf
    Schalk, Van der Merwe
    Frederik, Nevens
    JOURNAL OF HEPATOLOGY, 2019, 70 (01) : E130 - E130
  • [8] A SIMPLIFIED 6-MONTH PREDICTION SCORE FOR PRIMARY BILIARY CHOLANGITIS PATIENTS TREATED WITH URSODEOXYCHOLIC ACID
    Pinyopornpanish, Kanokwan
    Sarmini, Muhammad
    Khoudari, George
    Chadalavada, Pravallika
    Romero-Marrero, Carlos
    HEPATOLOGY, 2020, 72 : 733A - 734A
  • [9] Simplified 6-month prediction scores for primary biliary cholangitis patients treated with ursodeoxycholic acid
    Pinyopornpanish, Kanokwan
    Chadalavada, Pravallika
    Sarmini, Muhammad Talal
    Khoudari, George
    Alomari, Mohammad
    Padbidri, Vinay
    Romero-Marrero, Carlos
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2022, 34 (04) : 411 - 416
  • [10] Fenofibrate in Primary Biliary Cholangitis Patients With Inadequate Response to Ursodeoxycholic Acid (UDCA)
    Khaykis, Inessa
    Sherman, Alex
    Tobias, Hillel
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2018, 113 : S501 - S501