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The Epidemiology, Clinical, and Economic Burdens of Respiratory Syncytial Virus Infections Amongst Hospitalized Children Under 5 Years of Age in Jordan: A National Multi-Center Cross-Sectional Study
被引:0
|作者:
Abu-Helalah, Munir
[1
,2
]
Al-Shatnawi, Samah F.
[3
]
Abu Lubad, Mohammad
[4
]
Al-Zayadneh, Enas
[5
]
Jdaitawi, Hussein
[6
]
Harahsheh, Mea'ad
[7
]
AL-Iede, Montaha
[5
]
Nafi, Omar
[8
]
Yousef, Ruba
[9
]
Almaaitah, Ihsan
[10
]
Ababneh, Mai
[11
]
Alzubi, Toqa
Abu Mahfouz, Rand
[11
]
Adaylah, Heba
[11
]
Alhajaj, Hamzeh
[10
]
Tamimi, Mohammad Al
Drysdale, Simon B.
[12
,13
]
机构:
[1] Jordan Univ, Fac Med, Dept Family & Community Med, Amman 11942, Jordan
[2] Univ Jordan, Publ Hlth Inst, Amman 11942, Jordan
[3] Jordan Univ Sci & Technol, Fac Pharm, Dept Clin Pharm, Irbid 22110, Jordan
[4] Mutah Univ, Fac Med, Dept Microbiol & Pathol, Al Karak 61710, Jordan
[5] Univ Jordan, Fac Med, Amman 11942, Jordan
[6] Princess Rahma Hosp, Dept Pediat, Irbid, Jordan
[7] Univ Jordan, Sch Pharm, Amman 11942, Jordan
[8] Mutah Univ, Fac Med, Dept Obstet & Gynecol, Mutah 61710, Jordan
[9] King Hussein Canc Ctr, Dept Internal Med, Amman 11942, Jordan
[10] New Zarqa Govt Hosp, Dept Pediat, Zarqa, Jordan
[11] Univ Jordan, Amman 11942, Jordan
[12] Univ Oxford, Oxford Vaccine Grp, Dept Paediat, Oxford OX1 2JD, England
[13] NIHR Oxford Biomed Res Ctr, Oxford OX3 7JX, England
来源:
关键词:
RSV;
clinical;
epidemiological;
financial;
Jordan;
PNEUMONIA;
INFLUENZA;
RISK;
D O I:
10.3390/v16121867
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Respiratory syncytial virus (RSV) has been recognized as a highly important cause of morbidity and mortality among children and adults. A cross-sectional study at representative sites in Jordan was undertaken to provide an assessment of the epidemiology and health and economic burdens of RSV and influenza infections in Jordan amongst hospitalized children under 5 years old for the period between 15 November 2022 and 14 April 2023. This study involved 1000 patients with a mean age of 17.10 (SD: 16.57) months. Of these, half (n = 506, 50.6%) had positive results for RSV. Furthermore, 33% and 17.4% of the participants had positive results for RSV-B and RSV-A, respectively. The findings underscore the severity of RSV infections, where a significant proportion of the children experienced severe respiratory distress, which led to bronchiolitis and pneumonia. This study meticulously documented the clinical outcomes, including the need for intensive care, mechanical ventilation, and prolonged hospital stays. There was no statistically significant difference in the financial burdens between the RSV-positive and RSV-negative patients. This study revealed the urgent need for preventive measures to control the substantial burden of RSV among children under 5 years old in Jordan.
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页数:17
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