Chronic HDV infection is sustained by an intense HBsAg production fromintegrated HBV-DNA in the setting of a limited or even absent HBV reservoir

被引:0
|
作者
Salpini, Romina [1 ]
D'Anna, Stefano [2 ]
Piermatteo, Lorenzo [3 ]
Brancaccio, Giuseppina [4 ]
Teti, Elisabetta [5 ]
Di Lorenzo, Andrea [6 ]
Grossi, Ilaria [7 ]
Torre, Giulia [8 ]
Malagnino, Vincenzo [9 ]
Iannetta, Marco [6 ]
Silberstein, Francesca Ceccherini [7 ]
Pasquazzi, Caterina [10 ]
Cillo, Umberto [11 ]
Vitale, Alessandro [11 ]
Gringeri, Enrico [11 ]
Magrofuoco, Maria [11 ]
Pacenti, Monia [12 ]
Baiocchi, Leonardo [13 ]
Francioso, Simona [13 ]
Lenci, Ilaria [13 ]
Koffas, Apostolos [14 ]
Geretti, Anna Maria [15 ]
Abate, Maria Lorena [16 ]
Olivero, Antonella [16 ]
Gaeta, Giovanni Battista [17 ]
Sarmati, Loredana [15 ]
Rizzetto, Mario [16 ]
Gill, Upkar [14 ]
Kennedy, Patrick [14 ]
Caviglia, Gian Paolo [16 ]
Svicher, Valentina [18 ]
机构
[1] Tor Vergata Univ, Dept Biol, Rome, Italy
[2] Univ Roma Tor Vergata, Dept Expt Med, Rome, Italy
[3] Univ Roma Tor Vergata, Dept Biol, Rome, Italy
[4] Univ Padua, Dept Mol Med Infect Dis, Padua, Italy
[5] Univ Hosp Rome Tor Vergata, Infect Dis Unit, Rome, Italy
[6] Univ Roma Tor Vergata, Dept Syst Med Infect Dis, Rome, Italy
[7] Univ Roma Tor Vergata, Dept Expt Med, Rome, Italy
[8] Univ Roma Tor Vergata, Dept Biol, Rome, Italy
[9] Univ Roma Tor Vergata, Dept Syst Med Infect Dis, Rome, Italy
[10] Sant Andrea Hosp, Rome, Italy
[11] Univ Padua, Dept Surg Oncol & Gastroenterol, Hepatobiliary Surg & Liver Transplantat Unit, Padua, Italy
[12] Padova Univ Hosp, Microbiol & Virol Unit, Padua, Italy
[13] Policlin Tor Vergata, Hepatol Unit, Rome, Italy
[14] Queen Mary Univ London, Blizard Inst, Barts & London Sch Med & Dent, London, England
[15] Univ Roma Tor Vergata, Infect Dis Clin, Dept Syst Med, Rome, Italy
[16] Univ Turin, Dept Med Sci, Turin, Italy
[17] Univ L Vanvitelli, Infect Dis Unit, Naples, Italy
[18] Univ Roma Tor Vergata, Rtment Biol, Rome, Italy
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
OS-094
引用
收藏
页码:S59 / S60
页数:2
相关论文
共 50 条
  • [41] In HBeAg-negative chronic HBV infection, HBsAg levels profoundly vary among different HBV-genotypes and can be influenced by the degree of HBsAg variability: can quantitative HBsAg truly reflect intra-hepatic HBV reservoir?
    Salpini, R.
    Battisti, A.
    Anastasiou, O.
    Gill, U.
    Colagrossi, L.
    Bertoli, A.
    Fabeni, L.
    Fini, V.
    Piermatteo, L.
    Iuvara, A.
    Malagnino, V.
    Cerva, C.
    Lichtner, M.
    Mastroianni, C.
    De Sanctis, G.
    Paoloni, M.
    Marignani, M.
    Pasquazzi, C.
    Iapadre, N.
    Mari, T.
    Parruti, G.
    Vecchiet, J.
    Sarmati, L.
    Andreoni, M.
    Angelico, M.
    Grelli, S.
    Kennedy, P.
    Verheyen, J.
    Perno, C. F.
    Svicher, V.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S470 - S470
  • [42] INTERFERON FREE CLEARANCE OF HDV RNA AND HBsAg SEROCONVERSION IN A CIRRHOTIC SUBJECT WITH CHRONIC HBV / HDV CO-INFECTION WITH TDF AND REP 2165-MG
    Streinu-Cercel, Adrian
    Bazinet, Michel
    Elsner, Carina
    Dittmer, Ulf
    Vaillant, Andrew
    HEPATOLOGY, 2020, 72 : 505A - 506A
  • [43] Longitudinal changes in serum HBV-DNA levels during the natural course of HBeAg-negative chronic hepatitis B virus (HBV) infection
    Papatheodoridis, G. V.
    Sevastianos, V.
    Panopoulou, H.
    Chrysanthos, N.
    Hadziyannis, E.
    Cholongitas, E.
    Laras, A.
    Manesis, E. K.
    Hadziyannis, S. J.
    JOURNAL OF HEPATOLOGY, 2007, 46 : S182 - S182
  • [44] SERUM HBV-DNA TO DETECT CHRONIC HEPATITIS-B VIRUS-INFECTION IN MULTITRANSFUSED HEMOPHILIACS
    RUMI, MG
    COLOMBO, M
    BORTOLINI, M
    ROSSI, A
    ROMEO, R
    GRINGERI, A
    RATTI, G
    MANNUCCI, PM
    HEPATOLOGY, 1988, 8 (05) : 1429 - 1429
  • [45] REP 2139 monotherapy and combination therapy with pegylated interferon: safety and potent reduction of HBsAg and HDV RNA in Caucasian Patients with chronic HBV/HDV co-infection
    Bazinet, M.
    Pantea, V.
    Cebotarescu, V.
    Cojuhari, L.
    Jimbei, P.
    Vaillant, A.
    JOURNAL OF VIRAL HEPATITIS, 2015, 22 : 5 - 6
  • [46] SIGNIFICANT REDUCTION OF HBsAg AND HDVRNA BY THE NUCLEIC ACID POLYMER REP 2139 IN CAUCASIAN PATIENTS WITH CHRONIC HBV/HDV CO-INFECTION
    Bazinet, M.
    Pantea, V.
    Cebotarescu, V.
    Cojuhari, L.
    Jimbei, P.
    Vaillant, A.
    JOURNAL OF HEPATOLOGY, 2015, 62 : S257 - S258
  • [47] SERUM HBV-DNA (HEPATITIS-B VIRUS-DNA) IN ACUTE AND CHRONIC HEPATITIS-B INFECTION
    FEINMAN, SV
    BERRIS, B
    FAY, O
    SOOKNANAN, R
    TANNO, HE
    TUNG, WW
    LIEBERMAN, HM
    CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE, 1988, 11 (04): : 286 - 291
  • [48] The Evaluation of HBV-DNA Levels In Patients who Had Lost Hbsag After Recovery From Hepatitis B Virus Infection
    Motor, Vicdan Koksaldi
    Celikbas, Aysel Kocagsul
    Baykam, Nurcan
    Gok, Sebnem Eren
    Dokuzoguz, Basak
    VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, 2012, 18 (02): : 47 - 51
  • [49] Quantification of serum HBV-DNA with COBAS TaqMan for the diagnosis, monitoring and prognosis of chronic hepatitis B virus infection
    Hadziyannis, AS
    Panopoulou, H
    Laras, A
    Hadziyannis, ES
    Colucci, G
    Hadziyannis, SJ
    JOURNAL OF HEPATOLOGY, 2005, 42 : 147 - 147
  • [50] Undetectable serum HBV-DNA by quantitative PCR at the end of interferon treatment: A predictor of sustained responce and HBsAg clearance in patients with HBEAG-negative chronic hepatitis B.
    Manesis, EK
    Savas, S
    Alexopoulou, A
    Papakonstantinou, EJ
    Hadziyannis, J
    HEPATOLOGY, 1999, 30 (04) : 350A - 350A