Strategies for Survival of Staphylococcus aureus in Host Cells

被引:0
|
作者
Xu, Huiling [1 ]
Wang, Shengnan [1 ]
Liu, Xiaoting [1 ]
Li, Muzi [2 ]
Wang, Xiaozhou [1 ]
Chen, Huahua [2 ]
Qu, Chaonan [1 ]
Liu, Yongxia [1 ]
Liu, Jianzhu [1 ,2 ]
机构
[1] Shandong Agr Univ, Coll Vet Med, Tai An 271018, Peoples R China
[2] Shandong Agr Univ, Shandong Prov Key Lab Zoonoses, Tai An 271018, Peoples R China
关键词
<italic>Staphylococcus aureus</italic>; internalization; toxin; EVs; biofilms; SCVs; SMALL COLONY VARIANTS; EXTRACELLULAR VESICLES; ENDOTHELIAL-CELLS; ALPHA; INFECTION; TARGETS; SKIN; COLONIZATION; PERSISTENCE; MATURATION;
D O I
10.3390/ijms26020720
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Staphylococcus aureus, a common pathogen, is capable of producing a significant array of toxins and can develop biofilms or small colony variants (SCVs) to evade detection by the immune system and resist the effects of antibiotics. Its ability to persist for extended periods within host cells has led to increased research interest. This review examines the process of internalization of S. aureus, highlighting the impact of its toxins and adhesion factors on host cells. It elucidates the intricate interactions between them and the host cellular environment, thereby offering potential strategies for the treatment and prevention of S. aureus infections.
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页数:18
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