Overall survival and progression-free survival by PD-L1 status among endometrial cancer patients treated with pembrolizumab plus carboplatin/paclitaxel as compared to carboplatin/paclitaxel plus placebo in the NRG GY018 trial

被引:1
|
作者
Eskander, Ramez [1 ]
Sill, Michael [2 ]
Beffa, Lindsey [3 ]
Moore, Richard [4 ]
Hope, Joanie [5 ]
Musa, Fernanda [5 ]
Mannel, Robert [6 ]
Shahin, Mark [7 ]
Cantuaria, Guilherme [8 ]
Girda, Eugenia [9 ]
Mathews, Cara [10 ]
Kavecansky, Juraj [11 ]
Leath, Charles [12 ]
Gien, Lilian [13 ]
Hinchcliff, Emily [14 ]
Lele, Shashikant [2 ]
Landrum, Lisa [15 ]
Backes, Floor [16 ]
O'Cearbhaill, Roisin [17 ]
Liu, Rebecca [18 ]
Hill, Emily [19 ]
Thaker, Premal H. [20 ]
John, Veena [21 ]
Powell, Matthew [20 ]
Aghajanian, Carol
机构
[1] Univ Calif San Diego, La Jolla, CA 92093 USA
[2] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA
[3] Cleveland Clin, Cleveland, OH 44106 USA
[4] Univ Rochester, Med Ctr, Rochester, NY 14642 USA
[5] Pacific Canc Res Consortium NCORP, Seattle, WA USA
[6] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA
[7] Thomas Jefferson Univ, Willow Grove, PA USA
[8] Georgia NCI Community Oncol Res, Atlanta, GA USA
[9] Rutgers Canc Inst New Jersey, New Brunswick, NJ USA
[10] Women & Infants Hosp Rhode Isl, Providence, RI USA
[11] Kaiser Permanente, Walnut Creek, CA USA
[12] Univ Alabama Birmingham, Birmingham, AL USA
[13] Sunnybrook Hlth Sci Ctr, Odette Canc Ctr, Toronto, ON, Canada
[14] Northwestern Univ, Chicago, IL 60611 USA
[15] Indiana Univ, Indianapolis, IN 46204 USA
[16] Ohio State Univ, Columbus, OH 43210 USA
[17] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[18] Trinity Hlth IHA Med Grp, Michigan Canc Res Consortium NCORP, Ypsilanti, MI USA
[19] Univ Iowa, Iowa City, IA USA
[20] Washington Univ St Louis, St Louis, MO USA
[21] Northwell Hlth Canc Inst, Lake Success, NY USA
关键词
D O I
10.1016/j.ygyno.2024.07.015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
02 [LBA]
引用
收藏
页码:S5 / S5
页数:1
相关论文
共 38 条
  • [21] ABCB1 (MDR1) Polymorphisms and Progression-Free Survival among Women with Ovarian Cancer following Paclitaxel/Carboplatin Chemotherapy (vol 14, pg 5594, 2008)
    Johnatty, S. E.
    Beesley, J.
    Paul, J.
    Fereday, S.
    Spurdle, A. B.
    Webb, P. M.
    CLINICAL CANCER RESEARCH, 2012, 18 (01) : 319 - 320
  • [22] Progression-free survival 2-progression-free survival 1 in patients with primary advanced/recurrent endometrial cancer treated with dostarlimab plus chemotherapy compared with chemotherapy alone in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial
    Mccourt, Carolyn
    Ronzino, Graziana
    Shahin, Mark S.
    Kristeleit, Rebecca
    Willmott, Lyndsay
    Zub, Oleksandr
    Barlin, Joyce N.
    Gilbert, Lucy
    Cloven, Noelle
    Bjorge, Line
    Black, Destin
    Wymenga, Machteld
    Sharma, Sudarshan
    Gold, Michael A.
    Landrum, Lisa
    Mathews, Cara
    Antony, Grace
    Stevens, Shadi
    Powell, Matthew A.
    Mirza, Mansoor Raza
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_1) : A18 - A20
  • [23] Post hoc analysis of progression-free survival (PFS) and overall survival (OS) by mechanism of mismatch repair (MMR) protein loss in patients with endometrial cancer (EC) treated with dostarlimab plus chemotherapy in the RUBY trial.
    Mirza, Mansoor Raza
    Sharma, Sudarshan
    Roed, Henrik
    Landrum, Lisa M.
    Gilbert, Lucy
    Gold, Michael A.
    Novak, Zoltan
    Edelson, Mitchell
    Meirovitz, Mihai
    Diaz, John Paul
    Huygh, Greet
    Buscema, Joseph
    Pothuri, Bhavana
    Eshed, Helen Dinkelspiel
    Coleman, Robert L.
    Slomovitz, Brian M.
    Kostadinov, Rumen
    Stevens, Shadi
    Ronzino, Graziana
    Powell, Matthew A.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [24] Angiotensin-converting enzyme inhibitor prescription is associated with decreased progression-free survival (PFS) and overall survival (OS) in patients with lung cancers treated with PD-1/PD-L1 immune checkpoint blockers.
    Medjebar, Soleine
    Richard, Corentin
    Fumet, Jean-David
    Malo, Julie
    Elkrief, Arielle
    Blais, Normand
    Tehfe, Mustapha
    Florescu, Marie
    Boidot, Romain
    Truntzer, Caroline
    Routy, Bertrand
    Ghiringhelli, Francois
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [25] Non-small cell lung cancer patients treated with Anti-PD1 immunotherapy show distinct microbial signatures and metabolic pathways according to progression-free survival and PD-L1 status
    Dora, David
    Ligeti, Balazs
    Kovacs, Tamas
    Revisnyei, Peter
    Galffy, Gabriella
    Dulka, Edit
    Krizsan, Daniel
    Kalcsevszki, Regina
    Megyesfalvi, Zsolt
    Dome, Balazs
    Weiss, Glen J.
    Lohinai, Zoltan
    ONCOIMMUNOLOGY, 2023, 12 (01):
  • [26] Updated Overall Survival and PD-L1 Subgroup Analysis of Patients With Extensive-Stage Small-Cell Lung Cancer Treated With Atezolizumab, Carboplatin, and Etoposide (IMpower133)
    Liu, Stephen, V
    Reck, Martin
    Mansfield, Aaron S.
    Mok, Tony
    Scherpereel, Arnaud
    Reinmuth, Niels
    Garassino, Marina Chiara
    Carpeno, Javier De Castro
    Califano, Raffaele
    Nishio, Makoto
    Orlandi, Francisco
    Alatorre-Alexander, Jorge
    Leal, Ticiana
    Cheng, Ying
    Lee, Jong-Seok
    Lam, Sivuonthanh
    McCleland, Mark
    Deng, Yu
    Phan, See
    Horn, Leora
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (06) : 619 - +
  • [27] Durvalumab plus carboplatin/paclitaxel followed by durvalumab with or without olaparib as a firstline treatment for endometrial cancer: Overall survival and additional secondary efficacy en-dpoints by mismatch repair status in the DUO-E/GOG-3041/ ENGOT-EN10 Trial
    Baurain, Jean-Francois
    Chon, Hye Sook
    Pepin, Jessica Thomes
    Sundborg, Michael
    Gold, Michael
    Kim, Byoung-Gie
    Blank, Stephanie
    Liu, Ji-Hong
    McCollum, Michael
    Mori, Masahiko
    Jonuskiene, Goda
    Moore, Kathleen
    Novak, Zoltan
    Ramos Guette, Pedro Luis
    Joseph de Padua, Charles Andree
    Martin, Marta Gil
    Kowgier, Matthew
    del Rosario, Paula Michelle
    Westin, Shannon
    Van Nieuwenhuysen, Els
    GYNECOLOGIC ONCOLOGY, 2024, 190 : S62 - S63
  • [28] One-year progression-free survival in lung cancer patients treated with immune checkpoint inhibitors is significantly associated with a novel immunomodulatory signature but not PD-L1 staining
    Ranganath, Harsha
    Jain, Amit
    Smith, Justin
    Ryder, Julie
    Chaudry, Amina
    Miller, Emily
    Hare, Felicia
    Valasareddy, Poojitha
    Seitz, Rob
    Hout, David
    Schweitzer, Brock
    Nielsen, Tyler
    Mullins, Janice
    Vidal, Gregory
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [29] The effect of anemia on the progression-free survival in epithelial ovarian cancer (stage II-IV) patients treated with paclitaxel-carboplatin combination therapy: a retrospective analysis of the JGOG3016 trial of the Japanese Gynecologic Oncology Group (JGOG3016-A)
    Sugiyama, T.
    Kumagai, S.
    Shouji, T.
    Michimae, H.
    Katsumata, N.
    Tsuda, H.
    Aoki, D.
    Terauchi, F.
    Jobo, T.
    Yasuda, M.
    EJC SUPPLEMENTS, 2009, 7 (02): : 456 - 456
  • [30] IMpower130: Progression-free survival (PFS) and safety analysis from a randomized phase 3 study of carboplatin plus nab-paclitaxel (CnP) with or without atezolizumab as first-line (1L) therapy in advanced non-squamous NSCLC
    West, Howard L.
    McCleod, Michael
    Hussein, Maen
    Morabito, Alessandro
    Rittmeyer, Achim
    Conter, Henry J.
    Kopp, Hans-Georg
    Daniel, Davey
    McCune, Steven
    Mekhail, Tarek
    Zer, Alona
    Reinmuth, Niels
    Sadiq, Ahad
    Archer, Venice
    Lohmann, Tania Ochi
    Jessop, Helen
    Wang, Lijia
    Kowanetz, Marcin
    Sandler, Alan
    Cappuzzo, Federico
    CANCER RESEARCH, 2019, 79 (13)