Optimizing a mobile just-in-time adaptive intervention (JITAI) for weight loss in young adults: Rationale and design of the AGILE factorial randomized trial

被引:0
|
作者
Nezami, Brooke T. [1 ,2 ]
Valle, Carmina G. [1 ,2 ,3 ]
Wasser, Heather M. [1 ,2 ]
Hurley, Lex [4 ]
Hatley, Karen E. [3 ]
Tate, Deborah F. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Dept Nutr, 135 Dauer Dr,245 Rosenau Hall,CB 7461, Chapel Hill, NC 27599 USA
[2] Univ North Carolina Chapel Hill, Sch Med, 135 Dauer Dr,245 Rosenau Hall,CB 7461, Chapel Hill, NC 27599 USA
[3] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, 450 West Dr, Chapel Hill, NC 27599 USA
[4] Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Dept Hlth Behav, 135 Dauer Dr,170 Rosenau Hall,CB 7400, Chapel Hill, NC 27599 USA
[5] North Carolina Res Campus, Nutr Res Inst, 500 Laureate Way, Kannapolis, NC 28081 USA
基金
美国国家卫生研究院;
关键词
Young adults; Obesity; Overweight; Intervention; Weight management; Mobile; Adaptive interventions; SELF-DETERMINATION THEORY; PHYSICAL-ACTIVITY; RISK; GAIN; TECHNOLOGY; PROGRAM; DISEASE; WALKING; DELIVER; WOMEN;
D O I
10.1016/j.cct.2025.107808
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Young adults (YAs) are underrepresented in behavioral health and weight loss interventions and express interest in flexible, highly tailored programs. Mobile interventions are a lower-burden, scalable approach to providing behavioral support. Just-in-time-adaptive interventions (JITAI) promise to deliver the "right" support at the "right" time using real-time data from smartphones and sensors. JITAIs hold promise for promoting behavior changes needed for weight loss (dietary intake, activity, and self-weighing); however, there is limited evidence for selecting treatment components and levels of adaptation that are needed for success. Methods: The AGILE (Adaptive Goals and Interventions for Lifestyle Enhancement) trial utilizes the Multiphase Optimization Strategy (MOST) framework and a 25 full factorial experimental trial to test the efficacy of 5 intervention components, each with two levels, on weight loss among 608 YAs recruited from around the United States. All participants will receive a core 6-month weight loss intervention that includes evidence-based lessons, behavioral skills training, and daily weighing. With the goal of determining if greater adaptation leads to greater weight loss, we will test standard versus adaptive options of 5 additional intervention components: 1) diet monitoring approach (standard vs. simplified), 2) adaptive physical activity goals (weekly vs. daily), 3) decision points for message timing (fixed vs. adaptive), 4) decision rules for message content (standard vs. adaptive), and 5) message choice (no vs. yes). Assessments will occur at baseline, 3 months, and 6 months. Conclusions: Results of this trial will be used to create an optimized JITAI for weight loss in young adults.
引用
收藏
页数:8
相关论文
共 44 条
  • [41] Using a technology-based intervention to promote weight loss in sedentary overweight or obese adults: a randomized controlled trial study design
    Barry, Vaughn W.
    McClain, Amanda C.
    Shuger, Sara
    Sui, Xuemei
    Hardin, James W.
    Hand, Gregory A.
    Wilcox, Sara
    Blair, Steven N.
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2011, 4 : 67 - 77
  • [42] A Trauma-Informed, Geospatially Aware, Just-in-Time Adaptive mHealth Intervention to Support Effective Coping Skills Among People Living With HIV in New Orleans: Development and Protocol for a Pilot Randomized Controlled Trial
    Skeen, Simone J.
    Tokarz, Stephanie
    Gasik, Rayna E.
    Solano, Chelsea McGettigan
    Smith, Ethan A.
    Sagoe, Momi Binaifer
    Hudson, Lauryn, V
    Steele, Kara
    Theall, Katherine P.
    Clum, Gretchen A.
    JMIR RESEARCH PROTOCOLS, 2023, 12
  • [43] Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity
    Andrew McLeod
    Patricia Wolf
    Robert S. Chapkin
    Laurie A. Davidson
    Ivan Ivanov
    Michael Berbaum
    Lauren R. Williams
    H. Rex Gaskins
    Jason Ridlon
    Jen Sanchez-Flack
    Lara Blumstein
    Linda Schiffer
    Alyshia Hamm
    Kate Cares
    Mirjana Antonic
    Beatriz Penalver Bernabe
    Marian Fitzgibbon
    Lisa Tussing-Humphreys
    Trials, 24
  • [44] Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity
    McLeod, Andrew
    Wolf, Patricia
    Chapkin, Robert S.
    Davidson, Laurie A.
    Ivanov, Ivan
    Berbaum, Michael
    Williams, Lauren R.
    Gaskins, H. Rex
    Ridlon, Jason
    Sanchez-Flack, Jen
    Blumstein, Lara
    Schiffer, Linda
    Hamm, Alyshia
    Cares, Kate
    Antonic, Mirjana
    Bernabe, Beatriz Penalver
    Fitzgibbon, Marian
    Tussing-Humphreys, Lisa
    TRIALS, 2023, 24 (01)