The utility of animal models to inform the next generation of human space exploration

被引：0
|
作者：
Duporge, Isla [1 ,2 ]
Pereira, Talmo [3 ]
de Obeso, Santiago Castiello [4 ]
Ross, Julius G. Bright [5 ]
Lee, Stephen J. [2 ,6 ]
Hindle, Allyson G. [7 ]
机构：
[1] Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA
[2] Natl Acad Sci, Washington, DC 20418 USA
[3] Salk Inst Biol Studies, La Jolla, CA USA
[4] Yale Univ, Wu Tsai Inst, New Haven, CT USA
[5] Univ Oxford, Dept Biol, Wildlife Conservat Res Unit, Oxford, England
[6] US Army Res Lab, Army Res Off, Durham, NC USA
[7] Univ Nevada Las Vegas, Sch Life Sci, Las Vegas, NV USA
来源：
NPJ MICROGRAVITY | 2025年 / 11卷 / 01期
关键词：
SOCIAL-ISOLATION; MENTAL-HEALTH; BEHAVIOR; CONSEQUENCES; ENVIRONMENTS; CONFINEMENT; SPACEFLIGHT; PERFORMANCE; TARDIGRADES; PSYCHOLOGY;
D O I：
10.1038/s41526-025-00460-5
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Animals have played a vital role in every stage of space exploration, from early sub-orbital flights to contemporary missions. New physiological and psychological challenges arise with plans to venture deeper into the solar system. Advances in chimeric and knockout animal models, along with genetic modification techniques have enhanced our ability to study the effects of microgravity in greater detail. However, increased investment in the purposeful design of habitats and payloads, as well as in AI-enhanced behavioral monitoring in orbit can better support the ethical and effective use of animals in deep space research.
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页数：10
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