53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

被引:0
|
作者
Fradet-Turcotte, Amelie
Canny, Marella D.
Escribano-Diaz, Cristina
Orthwein, Alexandre
Leung, Charles C. Y.
Huang, Hao
Landry, Marie-Claude
Kitevski-LeBlanc, Julianne
Noordermeer, Sylvie M.
Sicheri, Frank
Durocher, Daniel
机构
[1] 600 University Avenue,Samuel Lunenfeld Research Institute, Mount Sinai Hospital
[2] University of Toronto,Department of Molecular Genetics
[3] University of Toronto,Department of Biochemistry
[4] University of Toronto,Department of Chemistry
关键词
D O I
10.1038/s41586-025-08696-7
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:E34 / E34
页数:1
相关论文
共 50 条
  • [31] TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
    Cescutti, Rachele
    Negrini, Simona
    Kohzaki, Masaoki
    Halazonetis, Thanos D.
    EMBO JOURNAL, 2010, 29 (21): : 3723 - 3732
  • [32] 53BP1 facilitates the ATM-dependent phosphorylation of APLF in the DNA damage response
    Fenton, Amanda L.
    Tran, Diana
    Koch, Christine Anne
    CANCER RESEARCH, 2014, 74 (19)
  • [33] 53BP1 is associated with replication protein A and is required for RPA2 hyperphosphorylation following DNA damage
    Yoo, E
    Kim, BU
    Lee, SY
    Cho, CH
    Chung, JH
    Lee, CH
    ONCOGENE, 2005, 24 (35) : 5423 - 5430
  • [34] 53BP1 is associated with replication protein A and is required for RPA2 hyperphosphorylation following DNA damage
    Eunjae Yoo
    Byung U Kim
    Seung Youn Lee
    Chae Hyun Cho
    Jay H Chung
    Chang-Hun Lee
    Oncogene, 2005, 24 : 5423 - 5430
  • [35] DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation
    Oda, Tsukasa
    Gotoh, Nanami
    Kasamatsu, Tetsuhiro
    Handa, Hiroshi
    Saitoh, Takayuki
    Sasaki, Nobuo
    CELL PROLIFERATION, 2023, 56 (06)
  • [36] DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation
    Oda, Tsukasa
    Gotoh, Nanami
    Kasamatsu, Tetsuhiro
    Handa, Hiroshi
    Saitoh, Takayuki
    Sasaki, Nobuo
    CANCER SCIENCE, 2024, 115 : 964 - 964
  • [37] Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage
    Etourneaud, Laure
    Moussa, Angela
    Rass, Emilie
    Genet, Diane
    Willaume, Simon
    Chabance-Okumura, Caroline
    Wanschoor, Paul
    Picotto, Julien
    Theze, Benoit
    Depagne, Jordane
    Veaute, Xavier
    Dizet, Elea
    Busso, Didier
    Barascu, Aurelia
    Irbah, Lamya
    Kortulewski, Thierry
    Campalans, Anna
    Le Chalony, Catherine
    Zinn-Justin, Sophie
    Scully, Ralph
    Pennarun, Gaelle
    Bertrand, Pascale
    SCIENCE ADVANCES, 2021, 7 (35):
  • [38] Phosphorylation of TIP60 Suppresses 53BP1 Localization a DNA Damage Sites
    Li, Mischa Longyin
    Jiang, Qinqin
    Bhanu, Natarajan, V
    Wu, Junmin
    Li, Weihua
    Garcia, Benjamin A.
    Greenberg, Roger A.
    MOLECULAR AND CELLULAR BIOLOGY, 2019, 39 (01)
  • [39] Cancer-associated 53BP1 mutations induce DNA damage repair defects
    Zhang, Jiajia
    Yan, Zhenzhen
    Wang, Yukun
    Wang, Yaguang
    Guo, Xin
    Jing, Ju
    Dong, Xiangnan
    Dong, Shasha
    Liu, Xiuhua
    Yu, Xiaochun
    Wu, Chen
    CANCER LETTERS, 2021, 501 : 43 - 54
  • [40] DNA Damage-Induced Phosphorylation of Histone H2A at Serine 15 Is Linked to DNA End Resection
    Ahmad, Salar
    Cote, Valerie
    Cote, Jacques
    MOLECULAR AND CELLULAR BIOLOGY, 2021, 41 (12)