Immunotherapy for hormone receptor‒positive HER2-negative breast cancer

被引:0
|
作者
Fatima Cardoso [1 ]
Kim M. Hirshfield [2 ]
Kimberly A. Kraynyak [2 ]
Konstantinos Tryfonidis [2 ]
Aditya Bardia [3 ]
机构
[1] Champalimaud Clinical Center/Champalimaud Foundation,Breast Unit
[2] Inc.,Merck & Co.
[3] Jonsson Comprehensive Cancer Center,Department of Medicine, Division of Hematology/Oncology, University of California Los Angeles
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D O I
10.1038/s41523-024-00704-9
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摘要
Additional therapies are needed to improve outcomes in patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative breast cancer. Research on the potential role of immunotherapy, particularly programmed cell death protein 1/programmed cell death ligand 1 inhibitors, is rapidly expanding in both the early and metastatic settings with some preliminary evidence suggesting benefit when used as part of combination therapy. Several ongoing phase 3 studies should help define their future role in treating these patients.
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