Increased potentiation of 5-fluorouracil induced thymidylate synthase inhibition by 5,10-methylenetetrahydrofolate (arfolitixorin) compared to leucovorin in patients with colorectal liver metastases; The Modelle-001 Trial

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作者
Helena Taflin [1 ]
Elisabeth Odin [2 ]
Göran Carlsson [1 ]
Bengt Gustavsson [2 ]
Oskar Hemmingsson [1 ]
Yvonne Wettergren [2 ]
Krzysztof Urbanowicz [1 ]
Jacek Turyn [2 ]
Ryszard T. Smolenski [3 ]
Godefridus J. Peters [1 ]
机构
[1] University of Gothenburg,Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy
[2] Department of Surgery,Region Västra Götaland, Sahlgrenska University Hospital
[3] Umeå University,Department of Diagnostics and Intervention/Surgery
[4] Medical University of Gdansk,Department of Biochemistry
[5] Vrije Universiteit Amsterdam,Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (Amsterdam UMC)
来源
BJC Reports | / 2卷 / 1期
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10.1038/s44276-024-00111-4
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