Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon

被引:0
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作者
Man Li [1 ]
Lisen Lu [2 ]
Qiuhong Bao [3 ]
Minghui Zhou [4 ]
Bin Nie [1 ]
Yanchao Liu [2 ]
Kai Shu [1 ]
Ting Lei [1 ]
Mingxin Zhu [1 ]
机构
[1] Huazhong University of Science and Technology,Department of Neurosurgery, Tongji Hospital, Tongji Medical College
[2] Huazhong University of Science and Technology,Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji
[3] Huazhong Agricultural University,College of Biomedicine and Health and College of Life Science and Technology
[4] Tiantai People’s Hospital of Zhejiang Province,Department of Oncology Medicine
关键词
Tertiary lymphoid structures; cGAS-STING; Exosomes; Stem cells; Glioma; Tumor microenvironment;
D O I
10.1186/s12951-025-03301-5
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