Spatial mapping of Alzheimer’s disease across genetic subtypesSpatial transcriptomics

被引：0
|
作者：
Alexi Nott [1 ]
Inge R. Holtman [2 ]
机构：
[1] Imperial College London,Department of Brain Sciences
[2] Imperial College London,UK Dementia Research Institute
[3] University Medical Center Groningen,Department of Biomedical Sciences, Section Molecular Neurobiology, University of Groningen
来源：
Nature Genetics | 2024年 / 56卷 / 12期
关键词：
D O I：
10.1038/s41588-024-01895-4
中图分类号：
学科分类号：
摘要：
Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer’s disease.
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页码：2592 / 2593
页数：1
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