Uveal melanoma with a GNA11/GNAQ mutation secretes VEGF for systemic spread

被引：0
|
作者：
Nguyễn Thị Thanh Nhàn [1 ]
Sanjay Ganesh [1 ]
Daniel E. Maidana [2 ]
Michael J. Heiferman [2 ]
Kaori H. Yamada [1 ]
机构：
[1] University of Illinois College of Medicine,Department of Pharmacology & Regenerative Medicine
[2] University of Illinois College of Medicine,Department of Ophthalmology & Visual Sciences
来源：
Signal Transduction and Targeted Therapy | / 10卷 / 1期
关键词：
D O I：
10.1038/s41392-025-02144-8
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations
    Gestrich, Catherine K.
    Vivero, Mathew P.
    Konczyk, Dennis J.
    Goss, Jeremy A.
    Labow, Brian I.
    Pearson, Gregory D.
    Cottrell, Catherine E.
    Mathew, Mariam T.
    Prasad, Vinay
    Kozakewich, Harry P.
    Fletcher, Christopher D. M.
    Greene, Arin K.
    Al-Ibraheemi, Alyaa
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2024, 48 (01) : 106 - 111
  • [42] GNA11 Mutation in a Patient With Cutaneous Origin Melanoma A Case Report
    Patel, Sapna P.
    Kim, Dae Won
    Lacey, Carol L.
    Hwu, Patrick
    MEDICINE, 2016, 95 (04)
  • [43] BRAF, KIT, NRAS, GNAQ and GNA11 mutation analysis in cutaneous melanomas in Turkish population
    Yilmaz, Ismail
    Gamsizkan, Mehmet
    Kucukodaci, Zafer
    Berber, Ufuk
    Demirel, Dilaver
    Haholu, Aptullah
    Narli, Gizem
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2015, 58 (03) : 279 - 284
  • [44] Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma
    M Dono
    G Angelini
    M Cecconi
    A Amaro
    A I Esposito
    V Mirisola
    I Maric
    F Lanza
    F Nasciuti
    S Viaggi
    M Gualco
    R Bandelloni
    M Truini
    D A Coviello
    S Zupo
    C Mosci
    U Pfeffer
    British Journal of Cancer, 2014, 110 : 1058 - 1065
  • [45] GNA11 joins GNAQ and GNA14 as a recurrently mutated gene in anastomosing hemangioma
    Liau, Jau-Yu
    Tsai, Jia-Huei
    Lan, Jui
    Chen, Chih-Chi
    Wang, Ying-Hao
    Lee, Jen-Chieh
    Huang, Hsuan-Ying
    VIRCHOWS ARCHIV, 2020, 476 (03) : 475 - 481
  • [46] Role of mutational status of GNAQ and GNA11 in the diagnosis of melanocytic tumors
    Narvaez-Martinez, Yislenz
    Sagrista-Garcia, Marc
    Teresa Fernandez-Figueras, Maria
    JOURNAL OF NEUROSURGERY, 2017, 126 (03) : 1024 - 1025
  • [47] Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma
    Dono, M.
    Angelini, G.
    Cecconi, M.
    Amaro, A.
    Esposito, A. I.
    Mirisola, V.
    Maric, I.
    Lanza, F.
    Nasciuti, F.
    Viaggi, S.
    Gualco, M.
    Bandelloni, R.
    Truini, M.
    Coviello, D. A.
    Zupo, S.
    Mosci, C.
    Pfeffer, U.
    BRITISH JOURNAL OF CANCER, 2014, 110 (04) : 1058 - 1065
  • [48] BRAF, KIT, NRAS, GNAQ and GNA11 Mutation Analysis in Common, Cellular and Malignant Blue Nevi
    Yilmaz, Ismail
    Gamsizkan, Mehmet
    Sari, Sule
    Demirkesen, Cuyan
    Heper, Aylin
    Yaman, Banu
    Calli, Aylin
    Narli, Gizem
    Kucukodaci, Zafer
    Berber, Ufuk
    Demirel, Dilaver
    Akalin, Taner
    Buyukbabani, Nesimi
    Demiriz, Murat
    MODERN PATHOLOGY, 2015, 28 : 128A - 128A
  • [49] GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi
    Vader, M. J. C.
    Madigan, M. C.
    Versluis, M.
    Suleiman, H. M.
    Gezgin, G.
    Gruis, N. A.
    Out-Luiting, J. J.
    Bergman, W.
    Verdijk, R. M.
    Jager, M. J.
    van der Velden, P. A.
    BRITISH JOURNAL OF CANCER, 2017, 117 (06) : 884 - 887
  • [50] Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma
    Ayturk, Ugur M.
    Couto, Javier A.
    Hann, Steven
    Mulliken, John B.
    Williams, Kaitlin L.
    Huang, August Yue
    Fishman, Steven J.
    Boyd, Theonia K.
    Kozakewich, Harry P. W.
    Bischoff, Joyce
    Greene, Arin K.
    Warman, Matthew L.
    AMERICAN JOURNAL OF HUMAN GENETICS, 2016, 98 (04) : 789 - 795
12345