AI-designed DNA sequences regulate cell-type-specific gene expression

被引：0
|
作者：
Pfenning, Andreas R. [1 ,2 ]
机构：
[1] Carnegie Mellon Univ, Computat Biol Dept, Pittsburgh, PA 15213 USA
[2] Carnegie Mellon Univ, Neurosci Inst, Pittsburgh, PA 15213 USA
来源：
NATURE | 2024年 / 634卷 / 8036期
关键词：
Genomics; Biotechnology; Synthetic biology; Machine learning;
D O I：
10.1038/d41586-024-03170-2
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Researchers have used artificial-intelligence models to create regulatory DNA sequences that drive gene expression in specific cell types. Such synthetic sequences could be used to target gene therapies to particular cell populations.
引用
收藏
页码：1059 / 1061
页数：3
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