Inhibiting hedgehog signal by a patched-1 antibody

被引:0
|
作者
Hu, Qinli [1 ]
Qi, Xiaofeng [1 ,2 ]
Donnelly, Linda [1 ]
Li, Xiaochun [1 ,3 ]
机构
[1] Univ Texas Southwestern Med Ctr, Dept Mol Genet, Dallas, TX 75390 USA
[2] Univ Texas Southwestern Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA
[3] Univ Texas Southwestern Med Ctr, Dept Biophys, Dallas, TX 75390 USA
关键词
D O I
10.1038/s41421-025-00772-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [41] A novel anti-Patched1 antibody can suppress hedgehog signaling pathway in human breast carcinoma cells
    Kubo, M.
    Nakamura, M.
    Kameda, C.
    Tanaka, H.
    Koga, K.
    Mikami, Y.
    Ikebe, M.
    Tanaka, M.
    Katano, M.
    BREAST CANCER RESEARCH AND TREATMENT, 2007, 106 : S282 - S282
  • [42] Hedgehog and Patched in neural development and disease
    Goodrich, LV
    Scott, MP
    NEURON, 1998, 21 (06) : 1243 - 1257
  • [43] Biochemical evidence that Patched is the Hedgehog receptor
    Marigo, V
    Davey, RA
    Zuo, Y
    Cunningham, JM
    Tabin, CJ
    NATURE, 1996, 384 (6605) : 176 - 179
  • [44] Transcriptional regulation of the hedgehog receptor patched
    Karpen, HE
    Bukowski, JT
    Vivatrat, N
    McLaughlin, L
    PEDIATRIC RESEARCH, 2004, 55 (04) : 95A - 95A
  • [45] Patched, the receptor of Hedgehog, is a lipoprotein receptor
    Callejo, Ainhoa
    Culi, Joaquim
    Guerrero, Isabel
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (03) : 912 - 917
  • [46] RETINOIC ACID-INDUCED PLACENTAL VASCULAR HYPOPLASIA WITH PATCHED-1 UP-REGULATION IN RATS
    Kajiwara, Kazuhiro
    Oishi, Yoshie
    Sato, Taisuke
    Matsuoka, Tomona
    Yamamura, Michihiro
    Udagawa, Haruhiko
    Inoue, Momoko
    Ito, Yuki
    Kamide, Taizan
    Wada, Seiji
    Akutsu, Hidenori
    Samura, Osamu
    Sago, Haruhiko
    Umezawa, Akihiro
    Okamoto, Aikou
    PLACENTA, 2018, 69 : E5 - E6
  • [47] The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development
    Katic, Jelena
    Loers, Gabriele
    Tosic, Jelena
    Schachner, Melitta
    Kleene, Ralf
    JOURNAL OF CELL SCIENCE, 2017, 130 (15) : 2606 - 2619
  • [48] Spectrum of mutations in the tumor-suppressor gene, patched-1, in patients with nevoid basal cell carcinoma syndrome
    Miyashita, T.
    NEURO-ONCOLOGY, 2007, 9 (02) : 183 - 183
  • [49] Molecular modelling of human PATCHED-1 may incentivize development of novel therapies for advanced basal cell carcinoma
    Hernandez, J.
    Kim, M.
    Kulkarni, V.
    Goode, M. A.
    Graham, S.
    Lane, M. P.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2024, 144 (08) : S144 - S144
  • [50] Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells
    De Rivoyre, Matthieu
    Ruel, Laurent
    Varjosalo, Markku
    Loubat, Agnes
    Bidet, Michel
    Therond, Pascal
    Mus-Veteau, Isabelle
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (39) : 28584 - 28595