Inhibiting hedgehog signal by a patched-1 antibody

被引:0
|
作者
Hu, Qinli [1 ]
Qi, Xiaofeng [1 ,2 ]
Donnelly, Linda [1 ]
Li, Xiaochun [1 ,3 ]
机构
[1] Univ Texas Southwestern Med Ctr, Dept Mol Genet, Dallas, TX 75390 USA
[2] Univ Texas Southwestern Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA
[3] Univ Texas Southwestern Med Ctr, Dept Biophys, Dallas, TX 75390 USA
关键词
D O I
10.1038/s41421-025-00772-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly
    Jeffrey E. Ming
    Michelle E. Kaupas
    Erich Roessler
    Han G. Brunner
    Mahin Golabi
    Mustafa Tekin
    Robert F. Stratton
    Eva Sujansky
    Sherri J. Bale
    Maximilian Muenke
    Human Genetics, 2002, 110 : 297 - 301
  • [2] Targeting the hedgehog signaling pathway with interacting peptides to Patched-1
    Nakamura, Masafumi
    Tanaka, Haruo
    Nagayoshi, Yousuke
    Nakashima, Hiroshi
    Tsutsumi, Kosuke
    Ohtsuka, Takao
    Takahata, Shunichi
    Tanaka, Masao
    Okada, Hidechika
    JOURNAL OF GASTROENTEROLOGY, 2012, 47 (04) : 452 - 460
  • [3] Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly
    Jeffrey E. Ming
    Michelle E. Kaupas
    Erich Roessler
    Han G. Brunner
    Mahin Golabi
    Mustafa Tekin
    Robert F. Stratton
    Eva Sujansky
    Sherri J. Bale
    Maximilian Muenke
    Human Genetics, 2002, 111 : 464 - 464
  • [4] Targeting the hedgehog signaling pathway with interacting peptides to Patched-1
    Masafumi Nakamura
    Haruo Tanaka
    Yousuke Nagayoshi
    Hiroshi Nakashima
    Kosuke Tsutsumi
    Takao Ohtsuka
    Shunichi Takahata
    Masao Tanaka
    Hidechika Okada
    Journal of Gastroenterology, 2012, 47 : 452 - 460
  • [5] Hedgehog Pathway Alterations Downstream of Patched-1 Are Common in Infundibulocystic Basal Cell Carcinoma
    Russell-Goldman, Eleanor
    MacConaill, Laura
    Hanna, John
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2021, 43 (04) : 266 - 272
  • [6] Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling
    Fleet, Andrew
    Lee, Jennifer P. Y.
    Tamachi, Aaliya
    Javeed, Imaan
    Hamel, Paul A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (34) : 17557 - 17568
  • [7] Changes in the protein expression of hedgehog and patched-1 in perisutural tissues induced by cranial distraction
    Nott, RL
    Stelnicki, EJ
    Mack, JA
    Ben, YX
    Mitchell, R
    Mooney, MP
    PLASTIC AND RECONSTRUCTIVE SURGERY, 2002, 110 (02) : 523 - 532
  • [8] Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
    Incardona, JP
    Lee, JH
    Robertson, CP
    Enga, K
    Kapur, RP
    Roelink, H
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) : 12044 - 12049
  • [9] Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly (vol 110, pg 297, 2002)
    Ming, JE
    Kaupas, ME
    Roessler, E
    Brunner, HG
    Golabi, M
    Tekin, M
    Stratton, RF
    Sujansky, E
    Bale, SJ
    Muenke, M
    HUMAN GENETICS, 2002, 111 (4-5) : 464 - 464
  • [10] Patched independent hedgehog signal transduction
    Ramirez-Weber, FA
    Casso, D
    Kornberg, TB
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 261A - 261A