Visible-light-induced radical cascade sulfonylation/cyclization towards indole-fused pyridine derivatives

被引：0
|
作者：
Du, Qin [1 ]
Pan, Ruohan [2 ]
Chen, Yu [2 ]
Tang, Yucai [2 ]
机构：
[1] Cent South Univ, Changde Hosp, Peoples Hosp Changde City 1, Xiangya Sch Med, Changde 415000, Peoples R China
[2] Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Engn Technol Res Ctr Key Preparat Technol Biomed P, Changde 415000, Peoples R China
来源：
RSC ADVANCES | 2025年 / 15卷 / 01期
关键词：
PHOTOREDOX CATALYSIS; ALKYNES SYNTHESIS; DIARYLSULFONES; INHIBITORS; CHLORIDES;
D O I：
10.1039/d4ra08000a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Indole-fused pyridines are an important motif in pharmaceuticals and functional molecules. A visible-light induced Ru(bpy)3Cl2<middle dot>6H2O catalyzed radical cascade sulfonylation/cyclization strategy for the synthesis of indole-fused pyridine derivatives was developed. Diverse indole-fused pyridines bearing different functional groups were obtained in moderate to good yields. Compared with previous work, the easily accessible starting materials, molecular nitrogen as byproduct, and eco-friendly visible light as an energy source all make this transformation more sustainable and practical.
引用
收藏
页码：216 / 222
页数：7
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