Solid-Phase Synthesis and Screening of Functional Peptides and Their Inhibitory Effects in Cancer Cells

被引:0
|
作者
Wu, Tai-Xia [1 ]
Cong, Hai-Lin [1 ,2 ]
Shen, You-Qing [1 ]
Yu, Bing [1 ]
机构
[1] Qingdao Univ, Inst Biomed Mat & Engn, Coll Chem & Chem Engn, Coll Mat Sci & Engn,State Key Lab Biofibers & Ecot, Qingdao, Peoples R China
[2] Shandong Univ Technol, Sch Mat Sci & Engn, Zibo, Peoples R China
基金
中国国家自然科学基金;
关键词
Functional peptides; solid-phase synthesis; antitumor effects;
D O I
10.1080/10584587.2024.2324679
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The inhibitory peptide library and functional short peptide RLFGKIW were synthesized by solid-phase synthesis and dichotomous method, and the inhibitory effect and cytocompatibility of the peptide library and peptide chain on breast cancer at the cellular level were evaluated by MTT method.
引用
收藏
页码:500 / 505
页数:6
相关论文
共 50 条
  • [41] Solid-phase synthesis of C-terminally modified peptides
    Ten Brink, Hefziba T.
    Meijer, Joris T.
    Geel, Remon V.
    Damen, Mark
    Lowik, Dennis W. P. M.
    Van Hest, Jan C. M.
    JOURNAL OF PEPTIDE SCIENCE, 2006, 12 (11) : 686 - 692
  • [42] Direct solid-phase synthesis of quinoxaline-containing peptides
    Staszewska, A
    Stefanowicz, P
    Szewczuk, Z
    TETRAHEDRON LETTERS, 2005, 46 (33) : 5525 - 5528
  • [43] SOLID-PHASE SYNTHESIS OF PEPTIDES WITH GROWTH-PROMOTING ACTIVITY
    CHILLEMI, F
    GAZZETTA CHIMICA ITALIANA, 1973, 103 (6-7): : 657 - 667
  • [44] CHEMICAL ASSEMBLY OF INORGANIC MATRICES FOR THE SOLID-PHASE SYNTHESIS OF PEPTIDES
    POSTNOV, VN
    KOLTSOV, SI
    JOURNAL OF APPLIED CHEMISTRY OF THE USSR, 1983, 56 (10): : 2222 - 2224
  • [45] An efficient method for the solid-phase synthesis of fluorescently labelled peptides
    Fernández-Carneado, J
    Giralt, E
    TETRAHEDRON LETTERS, 2004, 45 (31) : 6079 - 6081
  • [46] Solid-phase synthesis of azole-based peptides and peptidomimetics
    Biron, Eric
    Kessler, Horst
    UNDERSTANDING BIOLOGY USING PEPTIDES, 2006, : 100 - +
  • [47] REMOVAL OF PROTECTED PEPTIDES BY HYDRAZINOLYSIS AFTER SOLID-PHASE SYNTHESIS
    OHNO, M
    ANFINSEN, CB
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1967, 89 (23) : 5994 - &
  • [48] Peptides Derived from α-hydroxymethylserine: Aspects of solid-phase synthesis
    Marcin Stasiak
    Mirosław T. Leplawy
    Letters in Peptide Science, 1998, 5 : 449 - 453
  • [49] Peptides derived from α-hydroxymethylserine: Aspects of solid-phase synthesis
    Marcin Stasiak
    Mirosław T. Leplawy
    Letters in Peptide Science, 1998, 5 : 449 - 453
  • [50] Solid-phase synthesis of backbone-cyclized β-helical peptides
    Clark, Thomas D.
    Sastry, Mallika
    Brown, Christopher
    Wagner, Gerhard
    TETRAHEDRON, 2006, 62 (41) : 9533 - 9540