Epidemiology and pathogen characteristics of infections following solid organ transplantation

被引：0

作者：

Meng, Fanjie ^{[1
]}

Zhu, Chi ^{[2
,3
]}

Zhu, Chan ^{[2
,3
]}

Sun, Jiaxuan ^{[4
]}

Chen, Dongsheng ^{[2
,3
,5
]}

Ding, Ran ^{[2
,3
,5
]}

Cui, Liyuan ^{[1
,6
]}

机构：

[1] Yidu Cent Hosp Weifang, Clin Lab, Weifang 262500, Peoples R China

[2] Jiangsu Simcere Diagnost Co Ltd, State Key Lab Neurol & Oncol Drug Dev, Nanjing 210042, Peoples R China

[3] Nanjing Simcere Med Lab Sci Co Ltd, Dept Med, Nanjing 210042, Peoples R China

[4] Yale Univ, Yale Sch Publ Hlth, Dept Biostat, New Haven, CT 06520 USA

[5] Jinzhou Med Univ, Affiliated Hosp 1, Canc Ctr, Jinzhou 121001, Peoples R China

[6] Linyi Peoples Hosp, Dept Thorac Surg, Linyi 276000, Peoples R China

来源：

JOURNAL OF APPLIED MICROBIOLOGY | 2024年 / 135卷 / 12期

关键词：

solid organ transplantation; infection epidemiology; infection site; pulmonary infection; abdominal infection; bloodstream infection; INVASIVE FUNGAL-INFECTIONS; BLOOD-STREAM INFECTIONS; STAPHYLOCOCCUS-AUREUS BACTEREMIA; RESISTANT KLEBSIELLA-PNEUMONIAE; URINARY-TRACT-INFECTIONS; SINGLE-CENTER EXPERIENCE; GUILLAIN-BARRE-SYNDROME; RISK-FACTORS; LIVER-TRANSPLANTATION; CYTOMEGALOVIRUS-INFECTION;

D O I：

10.1093/jambio/lxae292

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Solid organ transplantation (SOT) recipients have a heightened risk for infection due to prolonged immunosuppressive drug use following transplant procedures. The occurrence of post-transplant infections is influenced not only by the transplanted organ type but also by varied factors. The kidney is the most common organ in SOT, followed by the liver, heart, and lung. This review aims to provide a comprehensive overview of the current epidemiological characteristics of infections after kidney, liver, heart, and lung transplantation, focusing on bacterial, fungal, and viral infections. The incidence and infection types demonstrated significant variability across different SOTs. Furthermore, this review attempts to elucidate the clinical characteristics of infections across patients following different SOTs and contribute to the development of individualized prevention strategies according to infection incidence, ultimately enhancing the quality of life of transplant recipients.

引用

页数：15

共 50 条

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