Plant-derived exosome-like nanoparticles in tissue repair and regeneration

被引：0
|
作者：
Gao, Canyu [1 ]
Chen, Yang [2 ]
Wen, Xingyue [3 ,4 ,5 ]
Han, Ruiying [3 ,4 ,5 ]
Qin, Yuxiang [1 ]
Li, Sijie [6 ]
Tang, Rong [3 ,4 ,5 ]
Zhou, Weikai [3 ,4 ,5 ]
Zhao, Junyu [3 ,4 ,5 ]
Sun, Jianxun [3 ,4 ,5 ]
Li, Zhengyong [6 ]
Tan, Zhen [7 ]
Wang, Deli [7 ]
Zhou, Changchun [1 ]
机构：
[1] Sichuan Univ, Coll Biomed Engn, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China
[2] Ctr Med Prod Tech Inspect, Chengdu 610015, Peoples R China
[3] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610041, Peoples R China
[4] Sichuan Univ, West China Hosp Stomatol, Natl Ctr Stomatol, Chengdu 610041, Peoples R China
[5] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Chengdu 610041, Peoples R China
[6] Sichuan Univ, West China Hosp, Dept Burn & Plast Reconstruct Surg, Chengdu 610041, Peoples R China
[7] Peking Univ, Shenzhen Hosp, Dept Bone & Joint Surg, Shenzhen 518036, Peoples R China
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2025年 / 13卷 / 07期
基金：
中国国家自然科学基金;
关键词：
DRUG-DELIVERY; NANOVESICLES; CELLS; HYDROGELS; COLITIS; TARGET; LEAVES;
D O I：
10.1039/d4tb02394c
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
This article reviews plant-derived exosome-like nanoparticles (ELNs), and highlights their potential in regenerative medicine. Various extraction techniques, including ultracentrifugation and ultrafiltration, and their impact on ELN purity and yield were discussed. Characterization methods such as microscopy and particle analysis are found to play crucial roles in defining ELN properties. This review is focused on exploring the therapeutic potential of ELNs in tissue repair, immune regulation, and antioxidant activities. Further research and optimization methods for extraction of ELNs to realize clinical potential applications are necessary.
引用
收藏
页码：2254 / 2271
页数：18
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