共 50 条
A red turn-on fluorescent probe reveals elevated H2O2 in cell anesthesia
被引:0
|作者:
Du, Longjie
[1
]
Ning, Yu
[1
]
Li, Wentao
[1
]
Kan, Jianfei
[1
,3
]
Li, Jianchun
[1
]
Wang, Jinhong
[1
]
Wang, Min
[2
]
Li, Yanxiang
[1
]
Zhou, Jin
[1
]
机构:
[1] Shandong Second Med Univ, Sch Pharm, Sch Basic Med Sci, Weifang 261053, Peoples R China
[2] Shandong Sunshine Union Hosp LLC, Weifang 261031, Peoples R China
[3] Shandong Daizhuang Hosp, Jining 272000, Peoples R China
基金:
中国国家自然科学基金;
关键词:
IN-VITRO;
KETAMINE;
D O I:
10.1039/d4cc05267f
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Cognitive dysfunction has become an important central nervous system (CNS)-related adverse reaction of intravenous anesthetics. Therefore, to further understand the role of H2O2, a potential marker of cognitive dysfunction, we constructed a fluorescent probe (LJ-1), which could specifically enable real-time detection of H2O2 in cells during anesthesia.
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页码:14443 / 14446
页数:4
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