A red turn-on fluorescent probe reveals elevated H2O2 in cell anesthesia

被引:0
|
作者
Du, Longjie [1 ]
Ning, Yu [1 ]
Li, Wentao [1 ]
Kan, Jianfei [1 ,3 ]
Li, Jianchun [1 ]
Wang, Jinhong [1 ]
Wang, Min [2 ]
Li, Yanxiang [1 ]
Zhou, Jin [1 ]
机构
[1] Shandong Second Med Univ, Sch Pharm, Sch Basic Med Sci, Weifang 261053, Peoples R China
[2] Shandong Sunshine Union Hosp LLC, Weifang 261031, Peoples R China
[3] Shandong Daizhuang Hosp, Jining 272000, Peoples R China
基金
中国国家自然科学基金;
关键词
IN-VITRO; KETAMINE;
D O I
10.1039/d4cc05267f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cognitive dysfunction has become an important central nervous system (CNS)-related adverse reaction of intravenous anesthetics. Therefore, to further understand the role of H2O2, a potential marker of cognitive dysfunction, we constructed a fluorescent probe (LJ-1), which could specifically enable real-time detection of H2O2 in cells during anesthesia.
引用
收藏
页码:14443 / 14446
页数:4
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