Samarium Diiodide/Samarium-Mediated Deoxygenative Hydrosilylation of Ketones

被引：0

作者：

Li, Ruxing ^{[1
]}

Ma, Yilin ^{[1
]}

Zhang, Jianwen ^{[1
]}

Liu, Chengwei ^{[1
]}

机构：

[1] Shanghai Univ, Dept Chem, Shanghai 200444, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 23期

关键词：

ELECTRON-TRANSFER REDUCTION; CHEMOSELECTIVE REDUCTION; ORGANIC-SYNTHESIS; SILYLATION; AMIDES; HYDROPHOSPHONYLATION; DERIVATIVES; COMPLEXES; ALDEHYDES; SMI2;

D O I：

10.1021/acs.joc.4c02052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first deoxygenative hydrosilylation of ketones promoted by samarium diiodide and samarium has been reported. In this approach, secondary alkyl silanes are synthesized from unactivated ketones and chlorosilanes in one step. The carbonyl group of ketones is activated by SmI2-mediated single-electron transfer process, which follows a deoxygenative elimination of O=Sm. Broad substrate scope and excellent functional group tolerance has been demonstrated.

引用

页码：17418 / 17424

页数：7

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