Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo

被引：0
|
作者：
Stec, David E.
Davisson, Robin L.
Haskell, Ronald E.
Davidson, Beverly L.
Sigmund, Curt D.
机构：
来源：
Journal of Biological Chemistry | / 274卷 / 30期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：21285 / 21290
相关论文
共 50 条
  • [41] Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice
    Zuo, Yuanbojiao
    Zhang, Chen
    Zhou, Yuan
    Li, Haiwen
    Xiao, Weidong
    Herzog, Roland W.
    Xu, Jie
    Zhang, Jifeng
    Chen, Y. Eugene
    Han, Renzhi
    CELL AND BIOSCIENCE, 2023, 13 (01):
  • [42] Cellular Analysis After Systemic Delivery of AAV8-GFP Under Control of Liver-Specific Promoter Elements Shows Transgene Expression in Hepatocytes and Liver Sinusoidal Endothelial Cells (LSECs)
    Lindgren, Jonathan R.
    Sabatino, Denise E.
    Fama, Rosella
    Nguyen, Giang
    Henriksen, Allysen
    Follenzi, Antonia
    Borroni, Ester
    MOLECULAR THERAPY, 2022, 30 (04) : 326 - 327
  • [43] Cell type-specific adenoviral transgene expression in the intact ovine pituitary gland after stereotaxic delivery:: An in vivo system for long-term multiple parameter evaluation of human pituitary gene therapy
    Davis, JRE
    McVerry, J
    Lincoln, GA
    Windeatt, S
    Lowenstein, PR
    Castro, MG
    McNeilly, AS
    ENDOCRINOLOGY, 2001, 142 (02) : 795 - 801
  • [44] A gene-delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer
    Oishi, Jun
    Jung, Joohee
    Tsuchiya, Akira
    Toita, Riki
    Kang, Jeong-Hun
    Mori, Takeshi
    Niidome, Takuro
    Tanizawa, Katsuyuki
    Kuroda, Shun'ichi
    Katayama, Yoshiki
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2010, 396 (1-2) : 174 - 178
  • [45] A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: Characterization and utility for in vivo studies of cyclophosphamide disposition
    Gu, Jun
    Wei, Yuan
    Fang, Cheng
    Xie, Fang
    Kannan, Kurunthachalam
    Yang, Weizhu
    Ding, Xinxin
    Chen, Chong-Sheng
    Waxman, David J.
    DRUG METABOLISM REVIEWS, 2006, 38 : 53 - 54
  • [46] A mouse model with liver-specific deletion and global suppression of the NADPH-Cytochrome P450 reductase gene: Characterization and utility for in vivo studies of cyclophosphamide disposition
    Gu, Jun
    Chen, Chong-Sheng
    Wei, Yuan
    Fang, Cheng
    Xie, Fang
    Kannan, Kurunthachalam
    Yang, Weizhu
    Waxman, David J.
    Ding, Xinxin
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2007, 321 (01): : 9 - 17
  • [47] expression of the human factor VIII transgene from dirloctocogene samoparvovec, a liver-specific recombinant adeno-associated virus gene therapy, for up to 72 weeks in adult mice
    Blanchard, E. L.
    Antrilli, T.
    Jones, G.
    Peterson, D. R.
    Rivera-Pena, G.
    Silverberg, J.
    Heinzel, E.
    Smith, S.
    Atkins, G.
    Frick, J.
    Li, C.
    Beck, H.
    Hanby, H.
    Alexander, J. M.
    Riling, C. R.
    HAEMOPHILIA, 2024, 30 : 45 - 46
  • [48] ESTABLISHMENT OF PFIC 3 MOUSE MODEL CARRYING HUMAN-LIKE BILE ACID COMPOSITION BY IN VIVO LIVER-SPECIFIC GENE DELETION USING ADENO-ASSOCIATED VIRUS AND CRISPR/Cas9 SYSTEM
    Tsuruya, Kota
    Kamiya, Akihide
    Mishima, Yusuke
    Arase, Yoshitaka
    Honda, Akira
    Kagawa, Tatehiro
    HEPATOLOGY, 2023, 78 : S113 - S115
  • [49] Liver-Specific Transcriptional Modules Identified by Genome-Wide In Silico Analysis Enable Efficient Gene Therapy in Mice and Non-Human Primates
    Chuah, Marinee K.
    Petrus, Inge
    De Bleser, Pieter
    Le Guiner, Caroline
    Gernoux, Gwladys
    Adjali, Oumeya
    Nair, Nisha
    Willems, Jessica
    Evens, Hanneke
    Rincon, Melvin Y.
    Matrai, Janka
    Di Matteo, Mario
    Samara-Kuko, Ermira
    Yan, Bing
    Acosta-Sanchez, Abel
    Meliani, Amine
    Cherel, Ghislaine
    Blouin, Veronique
    Christophe, Olivier
    Moullier, Philippe
    Mingozzi, Federico
    VandenDriessche, Thierry
    MOLECULAR THERAPY, 2014, 22 (09) : 1605 - 1613
  • [50] High-level gene expression of human factor VIII in vivo was achieved by a liver-specific construct containing ApoE-HCR and a heterologous intron.
    Miao, CH
    Ye, X
    Thompson, AR
    BLOOD, 2001, 98 (11) : 425A - 425A
12345