Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

被引:0
|
作者
Games, D.
Adams, D.
Alessandrini, R.
Barbour, R.
Berthelette, P.
Blackwell, C.
Carr, T.
Clemens, J.
Donaldson, T.
Gillespie, F.
Guido, T.
Hagopian, S.
Johnson-Wood, K.
Khan, K.
Lee, M.
et. al.
机构
来源
Nature | 1995年 / 373卷 / 6514期
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] The human amyloid-β precursor protein770 mutation V717F generates peptides longer than amyloid-β-(40-42) and flocculent amyloid aggregates
    Roher, AE
    Kokjohn, TA
    Esh, C
    Weiss, N
    Childress, J
    Kalback, W
    Luehrs, DC
    Lopez, J
    Brune, D
    Kuo, YM
    Farlow, M
    Murrell, J
    Vidal, R
    Ghetti, B
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (07) : 5829 - 5836
  • [22] Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease
    Schwab, C
    Hosokawa, M
    McGeer, PL
    EXPERIMENTAL NEUROLOGY, 2004, 188 (01) : 52 - 64
  • [23] Molecular and anatomic analysis of the PDGF-hAPP V717F transgenic mouse
    Hyman, BT
    Irizarry, MC
    McNamara, M
    Soriano, F
    Schenk, D
    Games, D
    NEUROLOGY, 1997, 48 (03) : 34003 - 34003
  • [24] Phenotypes of transgenic mice expressing the Alzheimer amyloid precursor protein.
    Hsiao, K
    BEHAVIOR GENETICS, 1997, 27 (06) : 593 - 593
  • [25] Neurodegeneration and gliosis in transgenic mice overexpressing a carboxy-terminal fragment of Alzheimer amyloid-beta protein precursor
    Sato, M
    Kawarabayashi, T
    Shoji, M
    Kobayashi, T
    Tada, N
    Matsubara, E
    Hirai, S
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 1997, 8 (05) : 296 - 307
  • [26] Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein
    Zhang, FY
    Eckman, C
    Younkin, S
    Hsiao, KK
    Iadecola, C
    JOURNAL OF NEUROSCIENCE, 1997, 17 (20): : 7655 - 7661
  • [27] Impaired neurotransmitter systems by Aβ amyloidosis in APPsw transgenic mice overexpressing amyloid β protein precursor
    Tomidokoro, Y
    Harigaya, Y
    Matsubara, E
    Ikeda, M
    Kawarabayashi, T
    Okamoto, K
    Shoji, M
    NEUROSCIENCE LETTERS, 2000, 292 (03) : 155 - 158
  • [28] Impaired eyeblink conditioning and decreased hippocampal volume in PDAPP V717F mice
    Weiss, C
    Venkatasubramanian, PN
    Aguado, AS
    Power, JM
    Tom, BC
    Li, L
    Chen, KS
    Disterhoft, JF
    Wyrwicz, AM
    NEUROBIOLOGY OF DISEASE, 2002, 11 (03) : 425 - 433
  • [29] Reduction in brain amyloid β burden and reversal of memory impairment in APP V717F transgenic mice following chronic administration of the anti-amyloid β antibody M266.2
    Gitter, BD
    Gannon, KS
    Cummins, DJ
    Brown-Augsburger, PL
    Bales, KR
    Bailey, DL
    Ballard, DW
    Brazelton, AD
    Czilli, DL
    Greene, SJ
    Hepburn, DL
    Schirtzinger, LM
    Yue, XM
    Paul, SM
    Galbreath, EJ
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S105 - S105
  • [30] Accumulation of amyloid-β protein in exocrine glands of transgenic mice overexpressing a carboxyl terminal portion of amyloid protein precursor
    Fukuchi, KI
    Li, L
    Hart, M
    Lindsey, JR
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2000, 81 (04) : 231 - 239