PIXE ANALYSIS OF TRACE ELEMENTS IN TISSUES OF RATS TREATED WITH ANTICONVULSANTS.

被引：0
|
作者：
Hurd, R.W. [1 ]
Van Rinsvelt, H.A. [1 ]
Kinyua, A.M. [1 ]
O'Neill, M.P. [1 ]
Wilder, B.J. [1 ]
Houdayer, A. [1 ]
Hinrichsen, P.F. [1 ]
机构：
[1] Veterans Administration Hospital,, Gainesville, FL, USA, Veterans Administration Hospital, Gainesville, FL, USA
来源：
Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms | 1986年 / B24-25卷 / pt 2 Apr III期
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SPECTROSCOPY; X-RAY;
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摘要：
Several lines of evidence implicate metals in epilepsy. Anticonvulsant drugs are noted to alter levels of metals in humans and animals. PIXE analysis was used to investigate effects of three anticonvulsant drugs on tissue and brain cortex trace elements. The content of zinc and copper was increased in liver and spleen of rats treated with anticonvulsants while selenium was decreased in cortex.
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页码：617 / 620
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