HIGH-PERFORMANCE LIGAND-EXCHANGE CHROMATOGRAPHY OF AMINO ACIDS ON CHIRAL STATIONARY PHASES.

被引：0
|
作者：
Carunchio, V. [1 ]
Messina, A. [1 ]
Sinibaldi, M. [1 ]
Fanali, S. [1 ]
机构：
[1] Univ 'La Sapienza', Rome, Italy, Univ 'La Sapienza', Rome, Italy
来源：
HRC & CC. Journal of high resolution chromatography & chromatography communications | 1988年 / 11卷 / 05期
关键词：
CHROMATOGRAPHIC ANALYSIS - Liquid - SILICA GEL;
D O I：
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中图分类号：
学科分类号：
摘要：
Three chiral stationary phases, obtained by grafting silica gel with (-)-trans-1,2-cyclohexanediamine, were studied for the resolution of alpha -amino acids by ligand-exchange chromatography. The packings were prepared by bonding the chiral ligand to silica gel via different hydrocarbon spacers. Separation of the optical isomers was accomplished by eluents containing a constant concentration of copper(II) acetate (0. 05mM). The elution sequence of amino acids was found to be dependent on the grafting reaction selected to prepare the chiral packings.
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页码：401 / 404
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