Isolation, purification and identification of the spermicidal active compound from neem oil

被引：0

作者：

Yin, Zhongqiong ^{[1
,2
]}

Gao, Ping ^{[1
]}

Gao, Rong ^{[1
]}

Jiang, Dehong ^{[1
]}

Liu, Kun ^{[1
]}

Liu, Shigui ^{[1
]}

机构：

[1] Lab. for Biol. Resource, Coll. of Life Sci., Sichuan Univ., Chengdu 610064, China

[2] Dept. of Veterinary Med., Southwest Agric. Univ., Chongqing 402460, China

来源：

High Technology Letters | 2004年 / 10卷 / 03期

关键词：

Bioassay - Fractionation - Purification - Spectroscopic analysis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Bioassay-directed fractionation of the chloroform extract of the neem oil has resulted in the isolation of new esters derivatives named 2-octadecanoic acid-4-palmitic acid-2,4-pentanediyl ester (compound 1). Its structure is deduced on the basis of spectroscopic evidence. The test of in vitro spermicidal activity of the compound 1 shows that the compound 1 can kill all sperms of Kunming mice in vitro in less than 20 sec at the concentration of 2 mg/ml.

引用

页码：44 / 46

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