An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

被引:0
|
作者
机构
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [11] Expression of mitotic spindle checkpoint protein hsMAD1 correlates with cellular proliferation and is activated by a gain-of-function p53 mutant
    Iwanaga, Y
    Jeang, KT
    CANCER RESEARCH, 2002, 62 (09) : 2618 - 2624
  • [12] Gain of function properties of mutant p53 proteins at the mitotic spindle cell cycle checkpoint
    Hixon, ML
    Flores, A
    Wagner, M
    Gualberto, A
    HISTOLOGY AND HISTOPATHOLOGY, 2000, 15 (02) : 551 - 556
  • [13] A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice
    Rajagopalan, Adhithi
    Feng, Yubin
    Gayatri, Meher B.
    Ranheim, Erik A.
    Klungness, Taylor
    Matson, Daniel R.
    Lee, Moon Hee
    Jung, Mabel Minji
    Zhou, Yun
    Gao, Xin
    Nadiminti, Kalyan V. G.
    Yang, David T.
    Tran, Vu L.
    Padron, Eric
    Miyamoto, Shigeki
    Bresnick, Emery H.
    Zhang, Jing
    JOURNAL OF CLINICAL INVESTIGATION, 2023, 133 (24):
  • [14] Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras
    Acin, Sergio
    Li, Zhongyou
    Mejia, Olga
    Roop, Dennis R.
    El-Naggar, Adel K.
    Caulin, Carlos
    JOURNAL OF PATHOLOGY, 2011, 225 (04): : 479 - 489
  • [15] NIPA Checkpoint Control In Oncogenic Transformation Is Dependent on p53
    Illert, Anna Lena
    Kawaguchi, Hiroyuki
    Albers, Corinna
    Sickinger, Melanie
    Keller, Ulrich
    Morris, Stephan W.
    Peschel, Christian
    Duyster, Justus
    BLOOD, 2010, 116 (21) : 1700 - 1700
  • [16] Gain-of-Function Mutations in p53 in Cancer Invasiveness and Metastasis
    Roszkowska, Katarzyna A.
    Gizinski, Slawomir
    Sady, Maria
    Gajewski, Zdzislaw
    Olszewski, Maciej B.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (04)
  • [17] Not all p53 gain-of-function mutants are created equal
    Mello, S. S.
    Attardi, L. D.
    CELL DEATH AND DIFFERENTIATION, 2013, 20 (07): : 855 - 857
  • [18] Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy
    Yue, Xuetian
    Zhao, Yuhan
    Xu, Yang
    Zheng, Min
    Feng, Zhaohui
    Hui, Wenwei
    JOURNAL OF MOLECULAR BIOLOGY, 2017, 429 (11) : 1595 - 1606
  • [19] Mutant p53: Gain-of-function oncoproteins and wild-type p53 inactivators
    Roemer, K
    BIOLOGICAL CHEMISTRY, 1999, 380 (7-8) : 879 - 887
  • [20] Gain-of-function mutant p53 in cancer progression and therapy
    Zhang, Cen
    Liu, Juan
    Xu, Dandan
    Zhang, Tianliang
    Hu, Wenwei
    Feng, Zhaohui
    JOURNAL OF MOLECULAR CELL BIOLOGY, 2020, 12 (09) : 674 - 687